Teaching

Poymer Materials Polymer Physics

Research projects

1. Name of the funding: An electric injectable hydrogel for myocardial infarction. Awarding Body: National Natural Science Foundation of China. DATE: Jan. 2015-Dec. 2018.  2. Name of the funding: The influence of anti-inflammatory scaffold on the growth, differentiation of stem cells under inflammatory conditions. Awarding Body: Natural Science Foundation of Tianjin. DATE: Apr. 2015-Mar. 2018.  3. Name of the funding: The influence of anti-inflammatory scaffold on the growth, differentiation of bone marrow mesenchymal stem cells under inflammatory conditions. Awarding Body: Ministry of Education doctoral of China. DATE: Jan. 2012-Dec. 2014. ��4. Name of the funding: The influence of anti-inflammatory scaffold on the differentiation of stem cells under inflammatory conditions. Awarding Body: National Natural Science Foundation of China. DATE: Jan. 2012-Dec. 2014.

Selected publications (Journal articles, patents and books)

2015 1. Lara Cutlar, Dezhong Zhou, Yongsheng Gao, Tianyu Zhao, Udo Greiser, Wei Wang, Wenxin Wang. Highly branched poly(beta-amino esters): synthesis and application in gene delivery. Biomacromolecules, 2015, DOI: 10.1021/acs.biomac.5b00966 2. Jianyuan Huang, Yongsheng Gao, Lara Cutlar, Jonathan O'Keeffe-Ahern, Tianyu Zhao, Feng-Huei Lin, Dezhong Zhou, Sean McMahon, Udo Greiser, Wei Wang, Wenxin Wang. Tailoring highly branched poly (�]-amino ester) s: a synthetic platform for epidermal gene therapy. Chem. Commun., 2015, 51 (40): 8473-8476 3. Xinyang Dai, Yinyu Zhang, Lina Gao, Tao Bai, Wei Wang, Yuanlu Cui, WenGuang Liu. A mechanically strong, highly stable, thermoplastic, and self-healable supramolecular polymer hydrogel. Advanced Materials, 2015, 27(23): 3566-3571 4. Junfei Song, Pengfei Zhang, Lu Cheng, Yue Liao, Bin Xu, Rui Bao, Wei Wang*, Wenguang Liu. Nano-silver in situ hybridized collagen scaffolds for regeneration of infected full-thickness burn skin. Journal of Materials Chemistry B 2015, 3 (20), 4231-4241 5. Pengfei Zhang, Xiufeng Hu, Lu Cheng, Wei Wang*, Wenguang Liu*. The recent development in reverse gene transfection. Progress in Chemistry, 2015, 27(1): 103-112 6. Yongmao Li, Jianhai Yang, Bin Xu, Fei Gao, Wei Wang, Wenguang Liu*. Enhanced Therapeutic siRNA to Tumor Cells by a pH-Sensitive Agmatine�VChitosan Bioconjugate. ACS applied materials & interfaces 2015, 7 (15), 8114-8124 2014 7. Wei Wang, Liang Sun, Pengfei Zhang, Junfei Song, Wenguang Liu*. An anti-inflammatory cell-free collagen/resvertrol scaffold for repairing osteochondral defects in rabbits. Acta Biomaterialia, 2014, 10(12) : 4983-4995  8. Xiufeng Hu, Lu Cheng, Ning Wang, Liang Sun, Wei Wang*, Wenguang Liu*. Surface passivated carbon nanodots prepared by microwave assisted pyrolysis: effect of carboxyl group in precursors on fluorescence properties. RSC Adv., 2014, 4, 18818-18826 9. Wei Wang, Lu Cheng, WenGuang Liu *. Biological applications of carbon dots. Science China Chemistry, 57(4), 522-539 10. Xiufeng Hu, Hongbo Wang, Jianhai Yang, Wenguang Liu*, Wei Wang*. Introducing Primary and Tertiary Amino Groups into a Neutral Polymer: A Simple Way to Fabricating Highly Efficient Nonviral Vectors for Gene Delivery. J. Appl. Polym. Sci. 2014, 131, 40468 11. Yongmao Li, Jianhai Yang, Liang Sun, Wei Wang, Wenguang Liu*. UV light-triggered unpacking of DNA to enhance gene transfection of azobenzene-containing polycations. J. Mater. Chem. B, 2014,2, 3868-3878  2013 12. Liang Sun, Sijie Zhang, Jinlong Zhang, Ning Wang, Wenguang Liu*, Wei Wang*. Fenton reaction-initiated formation of biocompatible injectable hydrogels for cell encapsulation. J. Mater. Chem. B, 2013,1: 3932-3939 13. Wei Wang, Wenjing Nan, Liang Sun, Wenguang Liu*. A systemic gene vector constructed by zwitterionic polymer modified low molecular weight PEI. React. Funct. Polym., 2013,73(8): 993-1000  14. Fengying Dai, Yuan Liu, Wei Wang*, Wenguang Liu. Stable gene transfection mediated by polysulfobetaine/PDMAEMA diblock copolymer in salted medium. J. Biomate. Sci., Polym. Edi. 2013, 24: 330-343  15. Wenjing Nan, Wei Wang, Han Gao�A Wenguang Liu*. Fabrication of a shape memory hydrogel based on imidazole-zinc ion coordination for potential cell-encapsulating tubular scaffold application. Soft matter 2013, 9: 132-137  2012 16. Ning Wang, Yanjiao Han, Yuan Liu, Tao Bai, Han Gao, Peng Zhang, Wei Wang*, Wenguang Liu*. High-strength hydrogel as a reusable adsorbent of copper ions. J. Hazard. Mater., 2012, 213: 258-264  17. Xinyun Zhai, Wei Wang, Chuandong Wang, Qin Wang, Wenguang Liu*. PDMAEMA-b-polysulfobetaine brushes-modified 3-polylysine as a serum-resistant vector for highly efficient gene delivery. J. Mater. Chem., 2012, 22:23576   18. Li Dan, Wang Wei, Guo Rui, Qi Yiying, Gou Zhongru, Gao Changyou*. Restoration of rat calvarial defects by poly(lactide-co glycolide)/hydroxyapatite scaffolds loaded with bone mesenchymal stem cells and DNA complexes. Chinese Science Bulletin, 2012, 57: 435-444 19. Changjun Liu, Peng Zhang, Xinyun Zhai, Feng Tian, Wenchen Li, Jianhai Yang, Yuan Liu, Hongbo Wang, Wei Wang, Wenguang Liu*. Nano-carrier for gene delivery and bioimaging based on carbon dots with PEI-passivation enhanced fluorescence. Biomterials 2012, 3(13): 3604-3613  20. Yuan Liu, Jianhai Yang, Peng Zhang, Changjun Liu, Wei Wang, Wenguang Liu*. ZnO quantum dots-embedded collagen/polyanion composite hydrogels with integrated functions of degradation tracking/inhibition and gene delivery. J. Mater. Chem. 2012, 22(2): 512-519  21. Tao Bai, Yanjiao Han, Peng Zhang, Wei Wang, Wenguang Liu*.  Zinc ion-triggered two-way macro-/microscopic shape changing and memory effects in high strength hydrogels with pre-programmed unilateral patterned surfaces. Soft matter, 2012, 8(25): 6846-6852   22. Jianhai Yang, Yuan Liu, Hongbo Wang, Lu Liu, Wei Wang, Chuandong Wang, Qin Wang, Wenguang Liu*. The biocompatibility of fatty acid modified dextran-agmatine bioconjugate gene delivery vector. Biomaterials, 2012, 33(2): 604-613   2011 23. Wei Wang, Bo Li, Changyou Gao*. Modulating the differentiation of BMSCs by surface properties of biomaterials. Progress in chemistry 2011, 23(10): 2160-2168  24. Wei Wang, Dan Li, Mei-cong Wang, Yang-lin Li, Chang-you Gao*. A hybrid scaffold of poly(lactide-co-glycolide) sponge filled with fibrin gel for cartilage tissue engineering. Chinese J. Polym. Sci. 2011, 29(2): 233-240  25. Peng Zhang, Jianhai Yang,  Wenchen Li,  Wei Wang,  Changjun Liu,  May Griffith ,Wenguang Liu*. Cationic polymer brush grafted-nanodiamond via atom transfer radical polymerization for enhanced gene delivery and bioimaging. J. Mater. Chem. 2011, 21(21): 7755-7764 2010 26. Wei Wang, Bo Li, Yanglin Li, Yangzi Jiang, Hongwei Ouyang, Changyou Gao. In vivo restoration of full-thickness cartilage defects by poly(lactide-co-glycolide) sponges filled with fibrin gel, bone marrow mesenchymal stem cells and DNA complexes. Biomaterials 2010, 31(23): 5953-5965   27. Wei Wang, Bo Li, Junzhou Yang, Long Xin, Yanglin Li, Hongpin Yin, Yiying Qi, Yangzi Jiang, Hongwei Ouyang, Changyou Gao. The restoration of full-thickness cartilage defects with BMSCs and TGF-beta 1 loaded PLGA/fibrin gel constructs. Biomaterials 2010, 31(34):8964-8973  28. Chen Zong, Deting Xue, Wenji Yuan, Wei Wang, Dan Shen, Xiangmin Tong, Dongyan Shi, Liyue Liu, Qiang Zheng, Changyou Gao, Jinfu Wang*. Reconstruction of rat calvarial defects with human mesenchymal stem cells and osteoblast-like cells in poly-lactic-co-glycolic acid scaffolds. European cells and Materials 2010, 20: 109-120   29. Jinfeng Yang, Cheng Cao, Wei Wang, Xiangmin Tong, Dongyan Shi, Fabai Wu, Qiang Zheng, Chunjuan Guo, Zhijun Pan, Changyou Gao, Jinfu Wang*. Proliferation and osteogenesis of immortalized bone marrow-derived mesenchymal stem cells in porous polylactic glycolic acid scaffolds under perfusion culture. J. Biomed. Mater. Res. 2010, 92A:817-829

• Designing the non-viral gene vectors or drug delivery system  Controlled/living polymerization techniques (ATRP and RAFT)
  
• Functional hydrogel for wound healing and myocardial infarction  
• Tissue engineering scaffolds for cartilage, bone, and heart tissue  Interaction between stem cells and biomaterials

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