李宁，女，理学博士，硕士生导师，天津大学卫生应急学院讲师。

主要研究方向为灾难医学领域创伤的致病机制、细胞死亡方式在疾病中的作用、免疫治疗及医学生物力学。作为课题负责人已主持多项国家级、省部级及校级课题。研究工作发表在Nature Communications、Nucleic Acids Research、Military Medical Research、Trends in Pharmacological Sciences、Cell death & Discovery、Pharmacological research等本领域重要期刊上。

• （1） 创伤损伤致病的分子机制
• （2） 免疫治疗
• （3） 机械力生物学

• 暂无内容

• Rescue RM/CS-AKI by blocking strategy with one-dose anti-myoglobin RabMAb.Nat Commun.2025,16 (1)
• Rosmarinic acid plus deferasirox inhibits ferroptosis to alleviate crush syndrome-related AKI via Nrf2/Keap1 pathway.Phytomedicine.2024,129
• Paving the way ahead: protocol optimization of mouse models in crush syndrome related acute kidney injury research.Frontiers in Phar....2024
• Special contribution of atomic force microscopy in cell death research.Nanotechnology Re....2024
• Potential therapeutic targets for trauma management.Trends in Pharmac....2023
• Delayed step-by-step decompression with DSF alleviates skeletal muscle crush injury by inhibiting NLRP3/CASP-1/GSDMD pathway.Cell death discov....2023
• Biotherapy of experimental acute kidney injury: emerging novel therapeutic strategies.Translation Resea....2023
• Ferroptosis in acute kidney injury following crush syndrome: A novel target for treatment.Journal of advanc....2023
• A Novel Rabbit Anti-Myoglobin Monoclonal Antibody′s Potential Application in Rhabdomyolysis Associated Acute Kidney Injury.International Jou....2023,24 (9)
• Myoglobin promotes macrophage polarization to M1 type and pyroptosis via the RIG-I/Caspase1/GSDMD signaling pathway in CS-AKI.Cell death discov....2022,8 (1)
• Pathway network of pyroptosis and its potential inhibitors in acute kidney injury.Pharmacological r....2022,175
• RIG-I, a novel DAMPs sensor for myoglobin, activates NF-κB/caspase-3 signaling in CS-AKI model.Military Medical ....2021,8 (1)
• Blocking MCT4 SUMOylation inhibits the growth of breast cancer cells. Molecular carcinogenesis.Molecular carcino....2021,60 (10)
• Emerging medical therapies in crush syndrome–progress report from basic sciences and potential future avenues.Renal Failure.2020,42 (1)
• The dynamics of forming a triplex in an artificial telomere inferred by DNA mechanics.Nucleic Acids Res.2019,47 (15)
• miR-21a negatively modulates tumor suppressor genes PTEN and miR-200c and further promotes the transformation of M2 macrophages.Immunol Cell Biol.2018,96 (1)
• PTEN inhibits macrophage polarization from M1 to M2 through CCL2 and VEGF-A reduction and NHERF-1 synergism.Cancer Biol Ther.2015,16 (2)