Xiaoli Wu
School
School of Life Sciences
Professional Title
Associate professor
Administrative Appointments
纳米生物医学教研组组长
Discipline
纳米生物医学
Contact Information
wuxiaoli@tju.edu.cn
Education Background
- Doctoral degree| Nankai University| Biochemistry and molecular biology | 2013
- Master’s Degree| Nankai University| Microbiology| 2010
- Bachelor’s Degree| Agricultural University of Hebei| Biotechnology| 2006
Research Interests
- 智能纳米药物调控肿瘤微环境免疫细胞功能
制备了系列响应肿瘤特征物质的光动力联合治疗纳米药物，可有效激活瘤内自然杀伤细胞/巨噬细胞/T细胞等，实现肿瘤的有效治疗 - 硒基纳米药物治疗炎症疾病的作用和机制：
基于纳米硒和抗炎中药小分子物质（如多酚等）开发了系列硒基纳米药物，用于调控炎性微环境中的巨噬细胞免疫代谢和分化，实现脑炎，脓毒症和肺炎的有效治疗。
Courses
Professional Membership
- 天津市神经科学学会 常务青年委员
- NBE杂志青年编委
Positions & Employments
-
2013.7-2019.12
School of Lifesciences | Tianjin Universtiy
Academic Achievements
- Papers
- [1] Synergistic anti-oxidative/anti-inflammatory treatment for acute lung injury with selenium based chlorogenic acid nanoparticles through modulating Mapk8ip1/MAPK and Itga2b/PI3k- AKT axis
- [2] Enabling AIEgens close assembly in tumor-overexpressed protein cluster for boosted image-guided cancer surgery
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- [3] A Novel Targeted and High-Efficiency Nanosystem for Combinational Therapy for Alzheimer’s Disease
- [4] Astragaloside III Enhances Anti-Tumor Response of NK Cells by Elevating NKG2D and IFN-γ
- [5] An NIR-responsive mesoporous silica nanosystem for synergetic photothermal-immunoenhancement therapy of hepatocellular carcinoma
- [6] Nanoparticle-based diagnostic and therapeutic systems for brain tumors
- [7] Activated γδ T cells exhibit cytotoxicity and the capacity for viral clearance in patients with acute hepatitis B
- [8] Upregulation of OX40 ligand on monocytes contributes to early virological control in patients with chronic hepatitis C: impact on sustained virological control
- [9] Decreased Vδ2 T cells associate with liver damage through regulating Th17 production in chronic hepatitis B patients
- Books
- [1] 1. Xiaoli Wu, Jiyuan Zhang, Yuanyuan Li, Ang Huang, Song Zhang, Fusheng Wang, Zhinan Yin Decreased V2 T cells associate with liver damage through regulating Th17 production in chronic hepatitis B patients J. Infectiouse Diseases 2013 Oct 15;208(8):1294-304
- [2] 2. Jiyuan Zhang, Xiaoli Wu, Bin Yang, Zheng Zhang, Fusheng Wang Upregulation of OX40 ligand on monocytes contributes to early virological control in patients with chronic hepatitis C: impact on sustained virological control European J. Immunology (co-author) 2013 Jul;43(7):1953-62
- Patents
- [1] 一种单宁酸-锌配位的壳聚糖-硒纳米颗粒的制备方法