Chen Ruibing
School
School of Pharmaceutical Science and Technology
Professional Title
Professor
Administrative Appointments
教授
Discipline
分析化学、药理学分析
Contact Information
rbchen@tju.edu.cn
Room 314-7, Building #24
Research Interests
- Pharmaceutical Biotechnology
- Small Molecules,Natural Products,Pharmaceutical Analysis
Professional Membership
- 中国农工民主党天津市委会委员
- 天津市欧美同学会理事
Positions & Employments
-
2010.1-2016.12
 Tianjin Medical University | Associate Professor  -
2016.12-2019.5
 Tianjin Medical University | Professor  -
2019.5-Now
 Tianjin University | Professor 
Academic Achievements
- Papers
- [1] 27. Qin G, Dang M, Gao H, Wang H, Luo F, Chen R*. Deciphering the protein-protein interaction network regulating hepatocellular carcinoma metastasis. Biochim Biophys Acta. 2017;1865(9):1114-1122.
- [2] 26. Chen R, Liu Y, Zhuang H, Yang B, Hei K, Xiao M, Hou C, Gao H, Zhang X, Jia C, Li L, Li Y*, Zhang N*. Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation. Nucleic Acids Res. 2017;45(17):9947-9959.
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- [3] 25. Hou C, Li Y, Liu H, Dang M, Qin G, Zhang N, Chen R*. Profiling the interactome of protein kinase C ζ by proteomics and bioinformatics. Proteome Sci. 2018;16:5.
- [4] 24. Wang H, Shao X, He Q, Wang C, Xia L, Yue D, Qin G, Jia C, Chen R*. Quantitative proteomics implicates Rictor/mTORC2 in cell adhesion. J Proteome Res. 2018;17(10):3360-3369.
- [5] 23. Li Y, Zhuang H, Zhang X,Li Y, Liu Y,Yi X, Qin G, Wei W*, Chen R*. Multi-omics integration reveals the landscape of pro-metastasis metabolism in hepatocellular carcinoma. Mol Cell Proteomics. 2018;17(4):607-618.
- [6] 22. Wang H, Jiang N, Zhang Y, Chen R*. Clinical proteomics: a driving force for cancer therapeutic target discovery and precision medicine. Cancer Biol Med. 2019;16(4):623-629.
- [7] 21. Yang B, Zhang Y, Hei K, Xiao M, Chen R*, Li Y*. Analysis of the non-specific binding proteins in the RNA pull-down experiment. Current Proteomics, 2020;17: 1-7.
- [8] 20. Dong X, Feng M, Yang H, Liu H, Guo H, Gao X, Liu Y, Liu R, Zhang N, Chen R*, Kong R*. Rictor promotes cell migration and actin polymerization through regulating ABLIM1 phosphorylation in Hepatocellular Carcinoma. Int J Biol Sci. 2020;16(15):2835-2852.
- [9] 19. Zhang Y, Guan X, Wang H, Wang Y, Yue D, Chen R*. Long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 regulates renal cancer cell migration via cofilin-1. Oncol Lett. 2020;20(4):53.
- [10] 18. Dang Y, Jiang N, Wang H, Chen X, Gao Y, Zhang X, Qin G, Li Y*, Chen R*. Proto-oncogene serine/threonine kinase PIM3 promotes cell migration via modulating Rho GTPase signaling. J Proteome Res. 2020;19(3):1298-1309.
- [11] 17. Wang C, Li Y, Yan S, Wang H, Shao X, Xiao M, Yang B, Qin G, Kong R, Chen R*, Zhang N*. Interactome analysis reveals that LncRNA HULC promotes aerobic glycolysis through LDHA and PKM2. Nat Commun. 2020;11(1):3162.
- [12] 16. Yan S, Zhao D, Wang C, Wang H, Guan X, Gao Y, Zhang X, Zhang N*, Chen R*. Characterization of RNA-binding proteins in the cell nucleus and cytoplasm. Anal Chim Acta. 2021;1168:338609.
- [13] 15. Wang H, Zhang Y, Guan X, Li X, Zhao Z, Gao Y, Zhang X, Chen R*. An integrated transcriptomics and proteomics analysis implicates lncRNA MALAT1 in the regulation of lipid metabolism. Mol Cell Proteomics. 2021;100141.
- [14] 14. Zhao D#, Wang C#, Yan S, Chen R*. Advances in the identification of long non-coding RNA binding proteins. Anal Biochem. 2021;639:114520.
- [15] 13. Wei J, Zhao Z, Luo F, Lan K, Chen R*, Qin G*. Sensitive and quantitative detection of SARS-CoV-2 antibodies from vaccinated serum by MoS2-field effect transistor. 2D Mater. 2022;9:015030. IF=6.861
- [16] 12. Wei J#, Zhao Z#, Lan K, Wang Z, Qin G*, Chen R*. Highly sensitive detection of multiple proteins from single cells by MoS2-FET biosensors. Talanta. 2022; 236:122839. IF=6.556
- [17] 11. Jiang N#, Gao Y#, Xu J, Luo F, Zhang X, Chen R*. A data-independent acquisition (DIA)-based quantification workflow for proteome analysis of 5000 cells. J Pharm Biomed Anal. 2022;216:114795. IF= 3.571
- [18] 10. Wang Z, Ma W, Wei J, Lan K, Yan S, Chen R*, Qin G*. High-performance olfactory receptor-derived peptide sensor for trimethylamine detection based on Steglich esterification reaction and native chemical ligation connection. Biosens Bioelectron. 2022;195:113673. IF=12.545
- [19] 9. Yang L, Wang H, Lu W, Yang G, Lin Z, Chen R*, Li H*. Quantitative proteomic analysis of oxaliplatin induced peripheral neurotoxicity. J Proteomics. 2022 Jul 10;266:104682. IF=3.855
- [20] 8. Xu J, Guan X, Jia X, Li H, Chen R*, Lu Y*. In-depth profiling and quantification of the lysine acetylome in hepatocellular carcinoma with a trapped ion mobility mass spectrometer. Mol Cell Proteomics. 2022 Jun 8;21(8):100255. IF=7.381
- [21] 7. Wang H, Shi X, Gao Y, Zhang X, Zhao H, Wang L, Zhang X, Chen R*. Polystyrene nanoplastics induce profound metabolic shift in human cells as revealed by integrated proteomic and metabolomic analysis. Environ Int. 2022 Jun 15;166:107349. IF=13.352
- [22] 6. Wang Z#, Ma W#, Wei J, Lan K, Yan S, Chen R*, Qin G*. Ultrasensitive Flexible Olfactory Receptor-Derived Peptide Sensor for Trimethylamine Detection by the Bending Connection Method. ACS Sens. 2022 Nov 10. doi: 10.1021/acssensors.2c01893. IF=9.618
- [23] 5. Wang H#, Chen L#, Qi L, Jiang N, Zhang Z, Guo H, Song T, Li J, Li H, Zhang N*, Chen R*. A single-cell atlas of tumor-infiltrating immune cells in pancreatic ductal adenocarcinoma. Mol Cell Proteomics. 2022 Jun 17;21(8):100258. IF=7.381
- [24] 4. Hou Y, Gao Y, Guo S, Zhang Z*, Chen R*, Zhang X*. Applications of spatially resolved omics in the field of endocrine tumors. Front Endocrinol (Lausanne). 2023 Jan 10;13:993081. IF=6.055
- [25] 3. Wei J, Liu Z, Zhang Z, Lan K, Wang Y, Chen R*, Qin G*. Suspended CNTs/MoS2 heterostructure field effect transistor for high performance biosensor and its application for serum PSA detection. Sensors and Actuators B: Chemical, 2023, 381, 133417. IF=9.221
- [26] 2. Ma W#, Wang Z#, Jiang D, Wei J, Yan J, Chen R*, Qin G*, Yan S*. An odorant receptor-derived peptide biosensor recognizing aggregation pheromone 4VA for efficient monitoring of the oriental migratory locust Locusta migratoria. Sensors and Actuators B: Chemical, 2023, 375, 132881. IF=9.221
- [27] 1. Wang Z#, Ma W#, Gao Z, Zhao Z, Du B, Wei J, Jiang D, Lan K, Chen R*, Yan S*, Qin G*. Sex Pheromone Receptor-Derived Peptide Biosensor for Efficient Monitoring of the Cotton Bollworm Helicoverpa armigera. ACS Sens. 2023 Jan 27;8(1):363-371. IF=9.618