李优鑫，副教授，博士生导师。长期从事药物分析教学与科研工作，在教学中，主持教学改革项目 10 项，参与天津市一流本科课程《药物分析》和校级课程思政项目建设，指导大学生创新创业训练计划项目 9 项，2024 年获得天津大学优秀师友导师称号，2025 年获得天津大学杰出师友导师提名奖。科研主要围绕前处理方法、色谱分离纯化介质、手性分析及酶分析等方向持续开展研究，目前已发表高水平科技论文 100 篇，获得发明专利 9 项，著书 1 个章节，主持和参与国家级、省部级等各类横纵向 30 余项。30 余本国际知名杂志通讯审稿人，《色谱》、《Journal of Analysis and Testing》和《分析测试学报》杂志青年编委，《Separations》客座编辑，《分析试验室》编辑。

• Li’s research addresses development of new techniques (such as HPLC, CE), chiral analysis, enzyme analysis, sample preparation, separation and purification of complex samples and their activities, and high throughput drug screening, and their applications.

• JAT 2025年度优秀青年编委，2025.
• 天津大学2025年“杰出师友导师提名奖”，2025.
• 天津大学第十三届优秀教案获得者，2025
• 天津市分析测试协会会员.
• 2024年天津大学优秀师友导师，2024.
• 天津大学第三届教师教学创新大赛优秀奖，2023.
• 天津大学本科生毕业论文优秀指导教师，2022.
• 天津市药品监督管理局专家库专家，2022.
• 王浩添，刘司婕、闫瑾丛、曹航，指导教师：李优鑫，全国大学生创新创业实验教学改革竞赛国际组特等奖，国家级，2018.
• 天津市第十三届青年教师教学基本功竞赛校内选拔赛，理科组，三等奖，2016.
• 第十届全国生物医药色谱及相关学术交流会，2014.4.19-22，山东·威海，优秀报告奖.
• Third annual SLAS Conference and Exhibition (SLAS2014), San Diego, CA, USA, 2014, January 18-22th, Tony B. Academic Travel Award.
• 天津大学“第九届青年教师讲课大赛”三等奖，2012.
• 天津大学药学院第三届青年教师讲课大赛，一等奖，2012.

• [33]Guirong Borijihan, Mimi Liu*, Mingming Bao, Fuquan Li, Youxin Li*, Meng He*, Ethylene glycol monopiperate: Synthesis, anti-hyperlipidemic activity, and pharmacokinetic study, Journal of Analytical Methods in Chemistry, 2026, In press.
• [32]Xinyu Xu, Guirong Borijihan, Mengqi Cheng, Yanmei Xu, Xiao Zhang, Xinru Wang, Yuchen Cui, Youxin Li*, Surface molecularly imprinted magnetic nanoparticles for selective enrichment of betamethasone in environmental and biological matrices, Journal of Analysis and Testing, 2026, In press.
• [31]Mengqi Cheng, Wanting Duan, Jiajia Fu, Ziyi Cheng, Xinru Wang, Ruijun Tang, Yanmen Xu, Yuchen Cui, and Youxin Li, Enhancing antioxidant activities of Orthosiphon aristatus extract via selective separation of rosmarinic acid and its analogues using multi-monomers rosmarinic acid-molecularly imprinted nanoparticles, Microchemical Journal, 2026, 228:119062.
• [30]Mengqi Cheng, Guirong Borijihan, Ruijun Tang, Xinru Wang, Yuchen Cui, Yanmei Xu, Ziyi Cheng, Jiajia Fu, Wanting Duan, Yunfei Du, Youxin Li*, Highly efficient and selective magnetic molecularly imprinted nanoparticles through multi-interactions for quercetin separation from complex matrices and antioxidant activity evaluation, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2026, 749:141326.
• [29]Xiaoqian Yuan†, Ziyi Cheng†, Jiajia Fu, Wanting Duan, Yuchen Cui, Ruijun Tang, Xinru wang, Youxin Li*, A synergy strategy of deep eutectic solvents and boric acid modified β-CD polymer for enhancing enantioseparation in HPLC, Analytica Chimica Acta, 2026, 1418:345876.
• [28]Wen Zhang, Yunuo Ren, Xiaoxi Liu, Xingmiao Liu, Weiwei Tang, Yingjie Ju, Wei Yu, Zhimou Guo, Huanhuan Qiao, Xiaoli Yu, Suxia Ren, Tianxiang Li, Yuqing Dong, Zengyi Huang, Youxin Li*, Zhiguang Yuchi*, Dong Li*, Yiwen Wang*, The medicine-food homology fruit Gouqi (Lycium barbarum L.) mitigates kidney stone via multiple bioactivities, Natural Product Communications, 2026, 21(5):1934578X261451343.
• [27]Ruijun Tang†, Ran Zhao†, Yuchen Cui, Xinru Wang, Yanmei Xu, Yiwen Wang*, and Youxin Li*, Efficient magnetic molecularly imprinted nanoparticle strategy for rapid lactic acid separation from fermentation broth, Microchemical Journal, 2026, 221:116805.
• [26]Xiao Zhang, Yuchen Cui, Wenjie Sui, Mengqi Cheng, Xinyu Xu, Wanting Duan, Ziyi Cheng, Jiajia Fu, Yanmei Xu*, Youxin Li*, Steam explosion as a green pretreatment strategy to enhance total phenolics release and biological activities in Potentilla discolor Bunge stems, Molecules, 2026, 31(1): 139.
• [25]Xiaoqian Yuan, Yuchen Cui, Yaqin Nan, Ruijun Tang, Xinru Wang, Yanmei Xu*, Xinghua Jin*, Yiwen Wang*, Ding Cheng*, and Youxin Li*, A combination strategy of HPLC and boric acid modified β-CD polymer for super-efficiently separating chiral substances with O/N atoms in chiral and/or adjacent carbons, Analytica Chimica Acta, 2025, 1378: 344687.
• [24]Pingyi Zheng, Xinru Wang, Ruijun Tang, Yuchen Cui, Xiaoqian Yuan, and Youxin Li*, An efficient strategy for quickly determining adenosine deaminase and purine nucleoside phosphorylase kinetics and screening their inhibitors, International Journal of Biological Macromolecules, 2025, 321: 146545.
• [23] Pingyi Zheng, Jipeng Liu, Xiao Zhang, Xiaoqian Yuan, Xinyu Xu, James J. Bao*, and Youxin Li*, One-step method for rapid determination of enzyme kinetics and inhibition constants through the improved capillary electrophoresis, Microchemical Journal, 2025, 215:114268.
• [22]Pingyi Zheng†, Xinru Wang†, Yuchen Cui, Ruijun Tang, Hongjian Yu*, Lin Wang*, and Youxin Li*, Fast determination of protein binding constants and sites to active flavonoids and phenolic acids by affinity capillary electrophoresis and fluorescence spectroscopy, Chemical Biology & Drug Design, 2025, 106(1): e70148.
• [21]Yanmei Xu, Laiming Li, Pingyi Zheng, Ran Zhao, Mengqi Cheng, Yanfang Su*, James J. Bao*, and Youxin Li*, Purification of mogroside V from crude extract of Siraitia grosvenorii using boronic acid-functionalized silica gel and its hypoglycemic activity determination, Separations, 2025, 12:135.
• [20]Yunuo Ren†, Wen Zhang†, Youxin Li†, Dekun Wang†, Weiwei Tang, Lingfei Wang, Xinghua Jin, Donghai Xia, Wei Yu, Yaodong Miao, Yingjie Ju, Shushen Sun, Tianxiang Li, Shaoshan Du*, Zhimou Guo*, Xiaoyue Tan*, Zhiguang Yuchi*, and Yiwen Wang*, Streamlined strategy for discovering active compounds for nephrolithiasis treatment from herbal medicines using the fruit fly model, Journal of Ethnopharmacology, 2025, 348:119846.
• [19]Ran Zhao, Ruijun Tang, Zhiyuan Shi, Yanmei Xu, Xiao Zhang, Xinyu Xu, Xiaoqian Yuan, Yuchen Cui, Xinru Wang, and Youxin Li*, Six silica absorbents with nitrogen and boronic acid groups for in-situ separation of lactic acid in real fermentation broth, Separation and Purification Technology, 2025, 364:132482.
• [18]Yaqin Nan†, Xiaoqian Yuan†, Xinyu Xu, Yanmei Xu, Xinghua Jin, and Youxin Li*, Boric acid modified β-CD polymer as chiral selector for chiral drug separation using gravity mediated capillary electrophoresis, Microchemical Journal, 2025, 210:112890.
• [17]Ran Zhao, Ling Zhang, Kun Zhang, and Youxin Li*, Reform and exploration of the experimental teaching mode of teaching assistant and group rotation system: taking pharmaceutical analysis experiment course as an example, Chinese Journal of Chromatography, 2025, 43(2):197-203.
• [16]Wenhui Jia, Pingyi Zheng, Yuchen Cui, James J. Bao, Yanmei Xu, and Youxin Li*, A convenient and efficient strategy for improving separation ability of capillary electrophoresis through tilting capillary as needed, Separations, 2024, 11(12): 340.
• [15]Haijiao Jia†, Yuchen Cui†, Xiaoqian Yuan, Yanmei Xu, and Youxin Li*, Magnetic Ru nanocatalysts for green solvent-free oxidation reactions of aromatic alcohols, Journal of Organometallic Chemistry, 2024, 1021:123354.
• [14]Haijiao Jia†, Xinyu Xu†, Yuchen Cui†, Mengqi Cheng, Guirong Borjihan, Xiao Zhang, Shengbo Yang, and Youxin Li*, Solvent-free oxidation of alcohols by a heterogeneous Fe3O4@SiO2-DTPA-Ru nanocatalyst, Inorganic Chemistry Communications, 2024, 169:103055.
• [13]Haijiao Jia, Xiao Zhang, Guirong Borjihan, Shengbo Yang, and Youxin Li*, A green and pollution-free heterogeneous ruthenium catalyst anchoring on magnetic nanoparticles with FPBA and DTPA groups for oxidation of aromatic alcohols, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2024, 698:134547.
• [12]Yaqin Nan†, Pingyi Zheng†, Xiaoqian Yuan, Xinyu Xu, Xiao Zhang, and Youxin Li*, An economic, accessible and stable sulphated cyclodextrin polymer as selector for efficiently separating chiral drugs in HPLC, Microchemical Journal, 2024, 204:110974.
• [11]Wenqing Zheng†, Pingyi Zheng†, Ran Zhao†, Xinyu Xu, Xiao Zhang, Xiaoqian Yuan, Ying Xu, Zichuan Liu*, and Youxin Li*, Fe3O4@SiO2-Protein A-oHSV/CD63 Ab for capturing virus and exosomes, Journal of Analysis and Testing, 2024, 8:335-350.
• [10]Haijiao Jia, Mengqi Cheng, Ran Zhao, Pingyi Zheng, Fangfang Ren, Yaqin Nan, Mengting Huang, and Youxin Li*, Excellent Pd-loaded magnetic nanocatalyst on multicarboxyl and boronic acid biligands, ACS Omega, 2024, 9: 17817-17831.
• [9]Wenqing Zheng, and Youxin Li*, Research progress of exosomes in the treatment of diabetes, Chinese Journal of Analysis Laboratory, 2024, 43(2): 229-237.
• [8]Mengqi Cheng†, Qianyi Song†, Xiaoyu Zhang†, Pingyi Zheng, Ran Zhao, Youxin Li*, and Haixia Chen*, Phenylboronic acid and amino bifunctional modified adsorbent for quickly separating phenolic acids from crude extract of Clerodendranthus spicatus and evaluation of their antioxidant and hypoglycemic activities, Molecules, 2023, 28:7539.
• [7]Wenqing Zheng, Ran Zhao, Haijiao Jia, Yaqin Nan, Pingyi Zheng, Mengqi Cheng, and Youxin Li*, Preparation of a novel polymer microspheres and application in solid phase extraction combined with hollow fiber membrane system for capturing lactic acid from simulated fermentation broth, Reactive & Functional Polymers, 2023, 193:105741.
• [6]Yaqin Nan, Pingyi Zheng, Mengqi Cheng, Ran Zhao, Haijiao Jia, Qinggang Liang, Youxin Li*, and James J. Bao*, Enhancement of chiral drugs separation by a novel adjustable gravity mediated capillary electrophoresis combined with sulfonic propyl ether β-CD polymer, Analytica Chimica Acta, 2023, 1279:341781.
• [5]Qianyi Song, Mengqi Cheng, Hongxu Liu, Haijiao Jia, Yaqin Nan, Wenqing Zheng, Youxin Li*, and James J. Bao, Preparation of a phenylboronic acid and aldehyde bi-functional group modified silica absorbent and applications in removing Cr(VI) and reducing to Cr(III), RSC Advances, 2023, 13: 15554-15565.
• [4]Jia Liu, Qianyi Song, Youxin Li*, and James J. Bao*, Development of a polyallylamine hydrochloride hydrogel imprinted with xylose for the purification of xylose from sugar mixture, International Journal of Food Science and Technology, 2023, 58(3): 1423-1433.
• [3]Jia Liu, Qianyi Song, Wenqing Zheng, Wenhui Jia, Haijiao Jia, Yaqin Nan, Fangfang Ren, James Jianmin Bao, and Youxin Li*, Preparation of boronic acid and carboxyl-modified molecularly imprinted polymer and application in a novel chromatography mediated hollow fiber membrane to selectively extract glucose from cellulose hydrolysis, Journal of Separation Science, 2022, 45 (13): 2415-2428.
• [2]Fangfang Ren, Simin Liu, Wenqing Zheng, Qianyi Song, Wenhui Jia, Yaqin Nan, Haijiao Jia, Jia Liu, James Jianmin Bao, and Youxin Li*, Preparation of a novel heterogeneous palladium nanocatalyst based on carboxyl modified magnetic nanoparticles and its applications in Suzuki-Miyaura coupling reactions, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2022, 642: 128611.
• [1]Assefa Aschenaki, Fangfang Ren, Jia Liu, Wenqing Zheng, Qianyi Song, Wenhui Jia, James Jianmin Bao, and Youxin Li*, Preparation of a magnetic and recyclable superparamagnetic silica support with boronic acid group for immobilizing Pd catalysts and it applications in Suzuki reactions, RSC Advances, 2021, 11(53), 33692-33702.