Liu Si
School
School of Life Sciences
Professional Title
Associate professor
Administrative Appointments
英才副教授
Contact Information
si.liu@tju.edu.cn
Education Background
- Doctoral degree| 浙江大学| 生物化学与分子生物学| 2018
- Bachelor’s Degree| 山东大学| 生物科学| 2012
Research Interests
- 蛋白质设计
- 蛋白质结构生物学
Positions & Employments
-
2020.5-Now
生命科学学院 | 天津大学 | 英才副教授 -
2019.6-2020.5
生命科学学院 | 天津大学 | 专职科研助理
Academic Achievements
- Papers
- [1] Pei Zhu, Mingxue Ma, Tianjie You, Bo Zhang, Sheng Ye*, Si Liu*, Optimizing prolyl hydroxylation for functional recombinant collagen in Escherichia coli, International Journal of Biological Macromolecules, 2024, 282(137400) (*equal corresponding)
- [2] Qiwei Wang, Sai Shi, Si Liu*, Sheng Ye*, A user-friendly fluorescent biosensor for precise lactate detection and quantification in vitro, ChemComm, 2024, 60, 12884-12887. (*equal corresponding)
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- [3] Mengyu Zhang, Xiangyao Wang, Junjie Wu, Qiwei Wang, Haozhe Cui, Xiaofeng Chen, Zhiming Zhao*, Si Liu*, Sheng Ye*, Preparation empty peptide-receptive MHC Class I complex for large-scale detection through photolabile peptide ligands, International Journal of Biological Macromolecules, 2024, 276(133781) (*equal corresponding)
- [4] Yanmei Liu; Jiayu Xu; Mingxue Ma; Tianjie You; Sheng Ye*; Si Liu*, Computational design towards a boiling-resistant single-chain sweet protein monellin, Food Chemistry, 2024, 440(138279). (*equal corresponding)
- [5] Pei Zhu; Tianjie You; Ying Wang; Mingxue Ma; Sheng Ye*; Si Liu*; A Cysteine-Maleimide-Based Design for Hemostatic, Antibacterial, and Biodegradable Wound Dressing, Bioconjugate Chemistry, 2024,35: 203−213. (*equal corresponding)
- [6] Xie, Yuan, Chang Shenghai, Zhao Cheng; Wang Feng, Liu Si*, Wang Jin, Delpire Eric, Ye Sheng, Guo Jiangtao, Structures and an activation mechanism of human potassium-chloride cotransporters, Science Advances, 2020, 6(50): 0-eabc5883.
- [7] Si Liu*, Shenghai Chang, Binming Han, Lingyi Xu, Mingfeng Zhang, Cheng Zhao, Wei Yang, Feng Wang, Jingyuan Li, Eric Delpire, Sheng Ye, Xiao-chen Bai, Jiangtao Guo, Cryo-EM structures of the human cation-chloride cotransporter KCC1, Science, 2019, 366:505–508.(*equal contribution)
- [8] Si Liu*, Lingyi Xu, Fenghui Guan, Yun-Tao Liu, Yanxiang Cui, Qing Zhang, Xiang Zheng, Guo-Qiang Bi, Z. Hong Zhou, Xiaokang Zhang & Sheng Ye, Cryo-EM structure of the human α5β3 GABAA receptor. Cell Research, 2018, 28:958–961.(*equal contribution)
- [9] Gu M, Liu Z, Lai R, Liu S*, Lin W, Ouyang C, Ye S, Huang H, Wang X, RKIP and TBK1 form a positive feedback loop to promote type I interferon production in innate immunity. EMBO J, 2016, 35(23):2553-2565.