School of Life Sciences, Medical College
Professor
Director of Institute of Nanobiomedicine
Nano-Biomedicine
022-87898212
022-87898212
jinchang@tju.edu.cn
#92, Weijin Road, Nankai District, Tianjin. China. School of Life Science, Tianjin University
300072
Jin Chang, Ph.D.
Professor and Doctoral Supervisor Director, Institute of Nanobiomedicine, School of Life Sciences, Tianjin University
Jin Chang is a Professor and Doctoral Supervisor at Tianjin University and Director of the Institute of Nanobiomedicine.
He is a recipient of the Special Government Allowance of the State Council of China, a Fellow of the Chinese Society of Biomedical
Engineering, and a recipient of the honorary title of National Outstanding Scientific and Technological Worker.
Professor Chang’s research focuses on nanobiomedicine and biomedical engineering, particularly the application of nanotechnology
to the diagnosis and treatment of major diseases. His research integrates micro- and nanobiosensing, biomaterials, targeted nanomedicine,
drug delivery, and immunotherapy, with an emphasis on translating fundamental discoveries into innovative diagnostic and therapeutic
technologies. His research has led to the development of nanomedicine platforms for Alzheimer’s disease, cancer immunotherapy,
smart polymeric drug delivery, and immunomodulatory nanomedicine, as well as intelligent micro/nanobiosensing technologies.
Professor Chang has led or participated in more than 60 major research projects, including projects supported by the National KeResearch and Development Program of China, the National High-Tech Research and Development Program (863 Program), and the
National Natural Science Foundation of China. His publications include papers in leading journals within the Cell, Nature, and Science (CNS)
journal families, with more than 70 publications in journals with impact factors exceeding 10 and over 10,000 citations to date. He holds
more than 50 granted Chinese invention patents, of which 12 have been licensed or transferred for commercialization.
Professor Chang has received the First Prize of the Tianjin Natural Science Award, three First Prizes of the Tianjin Science and Technology
Progress Award, and the Second Prize of the Huang Jiasi Biomedical Engineering Science and Technology Award, among other honors.
He has held leadership positions in major professional organizations, including the Chinese Society of Biomedical Engineering, Chinese
Society of Particuology, and Chinese Anti-Cancer Association, contributing to the advancement of nanomedicine, biomedical engineering,
and translational biomedical research.
- Posdoctoral Fellow| Tianjin University| Biochemistry Engineering| 1997
- Ph.D. | Nankai University| Polymer Chemistry| 1994
- M.D. | Tianjin Medical University| Nutrition and Food Hygine| 1991
- Bachelor| Tianjin Medical Universit| medicine| 1986
- Smart nano-molecular diagnosis in vitro
- Smart nano-probe of multi-modality imaging in vivo
- Anti-Alzheimer's nanomedicines
- Nanomedicines for ultrasound-mediated cancer immunotherapy
- Smart polymer nanomedicines
- Immunomodulatory nano-TCM (Traditional Chinese Medicine) formulations.
- Vice President of Chinese Society of Particles
- Director of Nanomedicine and Engineering Committee of Chinese Society of Biomedical Engineering
- President of Tianjin Society of Biomaterials.
- Honorary President of Tianjin Society of Biomedical Engineering
- Vice president of the Tianjin Neuroscience Society
- Director of Tianjin Engineering Research Center of Micro-Nanobiomaterials and Detective and Treatment Technology
- Director of Expert Advisory Committee of Life Science Societies Union, Tianjin Association of Science and Technology
- Fellow of the 9th Committee of Tianjin Association for Science and Technology
-
2016.11-2019.11
 Health Platform, Tianjin University | Associate Dean | Professor  -
2014.11-2026.10
 Institute of Nanobiomedicine, School of Life Science, Tianjin University | Director | Professor  -
2000.8-2002.5
 College of Pharmacy, University of Michigan, United States | Senior Visiting Scientist  -
1999.11-2014.10
 Institute of Nanobiotechnology,School of Material Science & Engineering, Tianjin UniversityTianjin University | Director | Professor  -
1997.3-1999.10
 Department of Polymeric Materials,School of Material Science & Engineering, Tianjin University | Associate Professor  -
1994.6-1995.3
 Institute of Polymer Chemistry, Nankai University | Assistant Research Fellow  -
1986.6-1988.8
 Tianjin Food Research Institute | Assistant Engineer 
- Papers
- [1] Nature Communications. 2024 , 15, 8346.(IF:18.1)
- [2] The Innovation, 2021, 2, 100160. (IF: 39.5)
-
- [3] Exploration.2025,5, 20240002. (IF: 30.4)
- [4] Science Advances, 2021, 7, eabc5267. (IF: 13.1)
- [5] Advanced. Materials. 2021, 33, 2007488. (IF: 27.4)
- [6] Advanced Materials, 2021, 33, 2100398 .(IF:27.4)
- [7] Advanced Materials, 2016, 28 (4): 707-714 .(IF:27.4)
- [8] Nano Today. 2021,38:101208. (IF:20.7)
- [9] Advanced Functional Materials, 2021, 31, 2006357.( IF: 16.8)
- [10] Advanced Functional Materials, 2018, 28, 1802026. ( IF: 16.8)
- [11] Advanced Functional Materials, 2018, 28(17): 1707291. ( IF: 16.8)
- [12] Advanced Functional Materials, 2011, 21, 1179-1186. ( IF: 16.8)
- [13] Advanced Science, 2020,7(19):1902906. ( IF: 15.8)
- [14] Advanced. Science. 2018, 5 , 1800295. (IF=15.8)
- [15] ACS nano 2021. doi.org/10.1021/acsnano.1c00135 (IF: 14.6)
- [16] ACS Nano, 2017, 11(12): 11898-11907. (IF:14.6)
- [17] ACS Nano, 2016, 10(10): 9637–9645. (IF:14.6)
- [18] ACS Nano 2016, 10, 2536−2548. (IF:14.6)
- [19] ACS Nano 2016, 10, 10245−10257. (IF:14.6)
- [20] ACS Nano, 2015,9(1): 488–495. (IF:14.6)
- [21] Matter 2021, 4, 26–53. (Partial IF: >12)
- [22] Biomaterials. 2021, 269,120654. (IF: 10.3)
- [23] Biomaterials, 2019, 199, 22-31. (IF :10.3)
- [24] Biomaterials, 2018, 161, 256-269. (IF: 10.3)
- [25] Biomaterials. 2010, 31,8741-8748. (IF:10.3)
- [26] Biomaterials, 2010,31, 6589-6596. (IF:10.3)
- [27] Biomaterials, 2010,31, 4129–4138. (IF:10.3)
- [28] Theranostics. 2020, 10, 6629-6637. (IF:11.6)
- [29] Theranostics, 2019, 9(1): .279-289( IF:11.6)
- [30] Theranostics, 2018, 8: 5870-5889. (IF:11.6)
- [31] Theranostics. 2013, 3(2): 99-108. (IF:11.6)
- [32] Acta Pharmaceutica Sinica B. 2021. (IF:11.4)
- [33] Biosensors and Bioelectronics, 2020,165: 112278. ( IF: 10.3)
- [34] Biosensors and Bioelectronics. 2017,97, 26-33. ( IF: 10.3)
- [35] Biosensors and Bioelectronics, 2011,30, 145-150. ( IF: 10.3)
- Books
- [1] 《Biomedical Engineering Technology》
- [2] 《New Delivery Systems for Controlled Drug Release from Natural Polymers》
- Patents
- [1] Application of Prussian blue nanoparticles in the preparation of drugs for preventing, delaying, and treating neurodegenerative diseases.
- [2] Prussian blue nanoparticles targeting Aβ senile plaques and a preparation method therefor
-
- [3] Albumin Nanoprobe Co-loaded with Multiple Alzheimer's Therapeutic Drugs and Preparation Method Thereof
- [4] A method for preparing peptide-loaded Prussian blue nanoparticles
- [5] A nanosized sonogenetic-sensitive microsphere, and a preparation method and application thereof.
- [6] A sound-controlled, visualizable micro/nano-carrier system for highly efficient synergistic tumor immunotherapy and its preparation method.
- [7] Method for ultrasensitive detection of miRNA based on poly(A) tailing and biocycling bioluminescence technology for non-diagnostic purposes
- [8] Method and kit for detecting miRNA-21 based on target-mediated isothermal cyclic amplification and nucleic acid test strip technology for non-diagnostic purposes
- [9] A method for labeling Influenza A virus nucleic acids based on rare-earth upconversion nanoprobes
- [10] Preparation and detection method of fluorescence quantitative high-sensitivity visualized joint detection immunochromatographic test strip based on magnetic enrichment
- [11] Preparation and detection method of high-sensitivity visualized bimodal acute myocardial infarction immunochromatographic test strip based on reverse fluorescence enhancement
- [12] Preparation method and application of blue up-transformation nano gene carrier doped with rare earth thulium element
- [13] Preparation method and application of red long afterglow gene nano carrier doped with rare earth praseodymium element
- [14] Preparation method of reduction-responsive targeting polymer micelle for mucus penetration
- [15] Preparation method of pH-responsive polymer micelle for mucus penetration
- [16] Method for preparing trans-anethole-albumin nanoparticles traced by indocyanine green fluorescence
- [17] Construction method of magneto-tribo-luminescence system
- [18] Preparation method of amphiphilic protein-polymer bond
- [19] Preparation method of novel polymer liposome based on bovine serum albumin-polycaprolactone.
- [20] Linoleic acid modified glucan and method for preparing polymer liposome
- [21] Preparation method of drug-loaded polylactic acid ultramicrobial
- [22] Preparation method of composite functional superfine magnetic carrier particles
- [23] Preparation method of a class of amphiphilic chitosan long-chain alkyl quaternary ammonium salt
- [24] A polymer liposome and its application
- [25] Preparation method of mitoxantrone nano-targeted sustained-release long-circulation liposome
- [26] Method for preparing inorganic/organic composite microspheres
- [27] Preparation method of composite drug-loaded microspheres, minocycline hydrochloride nanometer sustained-release composite drug-loaded microsphere system
- [28] A polymer liposomes and preparation method
- [29] A magnetic composite microspheres contained drugs and its preparation method
- [30] Polymer liposome based on polyamino acid and quaternary ammonium salt and preparation method
- [31] CuInS2 and CuInS2ZnS core-shell structure quantum dots with water-soluble zinc blende structure and preparation method
- [32] Magnetic fluorescent microsphere and preparation method
- [33] One kind of quantum dots entrapped composite of microspheres release system and preparation method
- [34] Lidocaine hydrochloride polymer liposome for surface anesthesia and preparation method
- [35] Hollow mesoporous silica nano particles and preparation method
- [36] Vincristine nano-targeting sustained-release long-circulating liposome and preparation method
- [37] Amphiphilic polymer modified oil-soluble core/shell quantum dots and preparation method
- [38] Lidocaine nano calcium phosphate preparation and preparation method
- [39] Mitoxantrone nano-calcium hydrogen phosphate preparation and preparation method
- [40] Minocyclic hydrochloride nano calcium carbonate preparation and preparation method
- [41] Preparation method and application of rare earth up-conversion drug release nano-carrier
- [42] Method and application for separate or simultaneous detection of iron ions and copper ions
- [43] Carboxyl functionalized micron-level rod-shaped up-conversion fluorescent material and preparation method
- [44] Targeting rare earth up-conversion gold core-shell nano-particle preparation methods
- [45] Preparation method of polystyrene-polyacrylic acid nano drug-loaded microspheres for photodynamic therapy
- [46] Controllable Curing Calcium Sulfate Bone Adhesive
- [47] Preparation method and application of folic acid-vincristine targeted sustained-release nano-microspheres
- Honors & Awards
- [1] Fellow of the Chinese Society of Biomedical Engineering
- [2] Special government allowance expert of the State Council
-
- [3] National Outstanding Scientist.
- [4] First Prize of Nature Science Award of Tianjin
- [5] First Prize of Scientific and Technological Progress Award of Tianjin
- [6] First Prize of Scientific and Technological Progress Award of Tianjin
- [7] First Prize of Scientific and Technological Progress Award of Tianjin
- [8] "Ten best supervisors in my mind" in Tianjin University




