Hyun Min Kim
School
School of Pharmaceutical Science and Technology
Professional Title
Associate professor
Administrative Appointments
Associate Professor
Contact Information
HKiM@tju.edu.cn
Building 24(SPST) Office B203, Lab 413
Education Background
- Postdoctoral | Harvard Medical School| Postdoctoral Genetics | 2016
- Doctoral degree| Georgia Institude of Technology| Molecular Biology | 2009
- Master’s Degree| Hanyang University| Biology, Microbiology | 1999
Research Interests
- 1.Investigating the roles of conserved Epigenetic regulators in DNA repair and damage response.
2.Investigating the role of novel and conserved gene of DNA repair and damage response. - We use a microscopic size nematode Caenorhabditis elegans as a model organism to study epigenetic control of DNA repair mechanism.
- We are interested in understanding the DNA repair mechanism in the germline. Especially, we have focused on investigating the epigenetic regulation of DNA damage response and repair.
Positions & Employments
-
2009.9-2016.6
Harvard Medical School | Research fellow -
2004.9-2009.6
Georgia Institute of Technology | Research and Teaching assistant -
1999.9-2003.6
Hanyang University Medical School | Research scientist -
1997.9-1998.6
Hanyang University | Research and Teaching assistant
Academic Achievements
- Books
- [1] Gao J, Barroso C, Zhang P, Kim HM, Li S, Labrador L, Lightfoot J, Gerashchenko MV, Labunskyy VM, Dong MQ, Martinez-Perez E, Colaiácovo MP.: N-terminal acetylation promotes synaptonemal complex assembly in C. Elegans. Genes & Development 30(21):2404-2416 • November 2016
- [2] Kim HM and Colaiácovo MP. CRISPR-Cas9-guided Genome Engineering in C. elegans. Current Protocols in Molecular Biology, 2016 July. http://onlinelibrary.wiley.com/doi/10.1002/cpmb.7/full
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- [3] Norris AD*, Kim HM*, Colaiácovo MP and Calarco JA. Efficient Genome Editing in Caenorhabditis elegans with a Toolkit of Dual Marker Selection Cassettes. 2015 Aug. Genetics. (*Co-first author)
- [4] Kim HM# and Colaiácovo MP#. DNA damage sensitivity assays in Caenorhabditis elegans. Bio-protocol (ISSN: 2331- 8325), 2015 Mar. (#Co-correspondence)
- [5] Kim HM and Colaiácovo MP. New Insights into the Post-Translational Regulation of DNA Damage Response and Double-Strand Break Repair in Caenorhabditis elegans. Genetics. 2015 Jun;200(2):495-504.
- [6] Kim HM and Colaiácovo MP. ZTF-8 interacts with the 9-1-1 complex and is required for DNA damage response and double-strand break repair in the C. elegans germline. PLOS Genet, 2014 Oct 10(10): e1004723.
- [7] Lu T, Aron L, Zullo J, Pan Y, Kim H, Chen Y, Yang TH, Kim HM, Drake D, Liu XS, Bennett DA, Colaiácovo MP, Yankner BA. ‘REST and stress resistance in ageing and Alzheimer's disease’, Nature, 2014 Mar 27;507(7493):448-54.
- [8] Saito TT, Lui DY, Kim HM, Meyer K, Colaiácovo MP. ‘Interplay between Structure-Specific Endonucleases for Crossover Control during Caenorhabditis elegans Meiosis’, PLOS Genet, 2013 Jul;9(7):e1003586.
- [9] Tang W, Dominska M, Greenwell PW, Harvanek Z, Lobachev KS, Kim HM, Narayanan V, Mirkin SM and Petes TD, 'Friedreich's ataxia (GAA)n(TTC)n repeats strongly stimulate mitotic crossovers in Saccharomyces cerevisae', PLOS Genet, Jan 2011, vol.7, pp.e1001270
- [10] Kim HM, Narayanan V, Mieczkowski PA, Petes TD, Krasilnikova MM, Mirkin SM and Lobachev KS, 'Chromosome fragility at GAA tracts in yeast depends on repeat orientation and requires mismatch repair', EMBO Journal, Nov 2008, vol.27, pp.2896-906
- [11] Narayanan V, Mieczkowski PA, Kim HM, Petes TD and Lobachev KS, 'The pattern of gene amplification is determined by the chromosomal location of hairpin-capped breaks', Cell, Jun 2006, vol.125, pp.1283-96
- [12] Kim HM, Ohn TB, Min BR and Choi YK, 'Sequence analysis and insertional inactivation of a gene encoding Moraxella sp. CK-1 cell wall hydrolase', Antonie Van Leeuwenhoek, June 2001, vol.79, pp.163-71
- Honors & Awards
- [1] Scholarship from Keystone Symposia on Molecular and Cellular Biology, March 1 2009.
- [2] Travel award from graduate research mentor for Undergraduate Research Scholar, Georgia Tech/Emory Center for the Engineering of Living Tissue, 2009.
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- [3] Sarstedt® Graduate Student Award for ‘Outstanding Accomplishments in Ph.D. research’, Dec 11 2008, Sandi Battista, Sarstedt, Inc.
- [4] Travel award from research mentor for Research Experience for Undergraduates 2007-2008.
- [5] Outstanding research paper of year 2001, Dec 2001, Chung-Ram association, Korea.
- [6] Graduate tuition scholarship, Hanyang University, 1998.
- [7] Undergraduate tuition scholarship, Hanyang University, 1994.
- [8] Scholarship from Keystone Symposia on Molecular and Cellular Biology, March 1 2009.
- [9] Travel award from graduate research mentor for Undergraduate Research Scholar, Georgia Tech/Emory Center for the Engineering of Living Tissue, 2009.
- [10] Sarstedt® Graduate Student Award for ‘Outstanding Accomplishments in Ph.D. research’, Dec 11 2008, Sandi Battista, Sarstedt, Inc.
- [11] Travel award from research mentor for Research Experience for Undergraduates 2007-2008.
- [12] Outstanding research paper of year 2001, Dec 2001, Chung-Ram association, Korea.
- [13] Graduate tuition scholarship, Hanyang University, 1998.
- [14] Undergraduate tuition scholarship, Hanyang University, 1994.
- [15] Scholarship from Keystone Symposia on Molecular and Cellular Biology, March 1 2009.
- [16] Travel award from graduate research mentor for Undergraduate Research Scholar, Georgia Tech/Emory Center for the Engineering of Living Tissue, 2009.
- [17] Sarstedt® Graduate Student Award for ‘Outstanding Accomplishments in Ph.D. research’, Dec 11 2008, Sandi Battista, Sarstedt, Inc.
- [18] Travel award from research mentor for Research Experience for Undergraduates 2007-2008.
- [19] Outstanding research paper of year 2001, Dec 2001, Chung-Ram association, Korea.
- [20] Graduate tuition scholarship, Hanyang University, 1998.
- [21] Undergraduate tuition scholarship, Hanyang University, 1994.