任翔（Xiang Ren, Ph.D.）

2010年8月获得Johns Hopkins大学硕士（电子工程）学位；2016年3月获得Drexel大学博士（机械工程）学位；

2016-2018：弗吉尼亚理工博后；2018-2021：圣母大学博后；2021-2022：圣母大学研究员；2022至今：天津大学副教授；研究方向：生物医学微机电系统（BioMEMS）。

任翔博士拥有物理与电子工程背景，多年来从事复合型微流控与生物医学微纳传感器系统领域研究。开发了复合型微流控检测系统，探测细胞级和亚细胞级的生物机械、电子、光学特性，完善了多物理特性“生物指纹”的概念，广泛用于乳腺癌、前列腺癌、以及脑肿瘤的诊断和抗癌药药效分析，循环肿瘤细胞检测；同时将BioMEMS技术用于开发细胞级生物计算领域的应用，将合成生物学与微电子和生物机械领域结合在一起，开发出了一系列“后摩尔时代”的新型计算方式：半导体合成生物学计算（Semiconductor Synthetic Biocomputing, SemiSynBio）。成果先后发表在Lab on a Chip, ACS Sensors, Analytical Chemistry,  Biomicrofluidics, Microsystems & Nanoengineering, Nano Letters, Biosensors & Bioelectronics, Sensors and Actuators B, Small, Advanced Intelligent Systems。在圣母大学期间，与著名学者、终身成就奖获得者Hsueh-Chia Chang和2019年美国总统奖获得者Pinar Zorlutuna合作开发MIX.miR传感器，并用姓名缩写（XR）命名，实现了高通量miRNA检测，用于研究急性心肌梗死。在Drexel大学期间，将增材制造技术结合在微流和合成生物学领域，使用聚合物制造了可进行光合作用的人造细胞，模拟植物细胞功能，吸收光能、CO2和水，合成葡萄糖，凭借博士期间这项成果，获得杰出奖。结合微电子学院的强项，将这类复合型微纳电子机械系统进一步演变成便携的智能化系统，延续拓展下一代半导体合成生物学计算的新概念、新原理和新器件。将传统的芯片实验室“Lab-on-Chip (LOC)”概念推进到未来的家庭芯片实验室“Lab-at-Home (L@H)”概念，同时延伸对COVID-19后遗症及对多器官长期影响的研究课题。

Xiang Ren received the B.S. degree in electrical engineering from the University of Electronic Science and Technology of China, Chengdu, China, in 2009, the M.S. degree in electrical and computer engineering from Johns Hopkins University, Baltimore, MD, USA, in 2010, and the Ph.D. degree in mechanical engineering and mechanics from Drexel University, Philadelphia, PA, USA, in 2016. He was a Research Assistant with the Advanced Manufacturing Laboratory and BioMEMS and Lab-on-a-Chip Laboratory, Drexel University. Dr. Ren received the Outstanding Promise Award upon graduation of Ph.D. from Drexel University. He continued as a post-doctoral researcher in electrical and computer engineering with the VT-MEMS Laboratory, Virginia Tech, Blacksburg, VA, and a postdoctoral and research scientist in aerospace and mechanical engineering with the tissue engineering laboratory, University of Notre Dame, IN. He is currently an assistant professor with the BioMEMS laboratory in the Department of Microelectronics, Tianjin University, China. His research interests are advanced BioMEMS, biosensing, microfluidics, synthetic biology, and additive manufacturing.

Research Group website:

https://www.x-mol.com/groups/tju-biomems?lang=en

• 半导体合成生物学
• 亚细胞级传感器
• 微纳电子机械系统
• 可编程流体 & 3D/4D打印

• 2010~2011 Drexel Dean's Fellowship
• 2012 National Science Foundation Division of Civil, Mechanical & Manufacturing Innovation (CMMI) Annual Meeting Fellowship (June. 2012, NSF)
• Drexel IEEE Graduate Forum's 6th Annual Research Poster Symposium poster competition 3rd place winner (March. 2014, Drexel)
• 2014 Doctoral Research Excellence (June. 2014, Drexel)
• Drexel IEEE Graduate Forum's 8th Annual Research Poster Symposium poster competition 2nd place winner (March. 2016, Drexel)
• Outstanding Promise Award (May. 2016, Drexel)

• Jiaying Ji, Xiang Ren, Jorge Gomez, Mohammad Khairul Bashar, Nikhil Shukla, Suman Datta, and Pinar Zorlutuna*, Large-Scale Cardiac Muscle Cell-Based Coupled Oscillator Network for Vertex Coloring Problem, Advanced Intelligent Systems, 2023, vol.5, iss.5, 2200356.
• Gozde Basara, Gokhan Bahcecioglu, Xiang Ren, Pinar Zorlutuna*, An Experimental and Numerical Investigation of Cardiac Tissue-Patch Interrelation, Journal of Biomedical Engineering, 2023, vol.145, 081004.
• Xin Geng, Zi-Ang Zhou, Yang Mi, Chunhong Wang, Meng Wang, Chenjia Guo, Chongxiao Qu, Shilun Feng, Inyoung Kim, Miao Yu, Hongming Ji*, Xiang Ren*, Glioma Single-Cell Biomechanical Analysis by Cyclic Conical Constricted Microfluidics, Analytical Chemistry, 2023, vol.95, iss.42, 15585-15594.
• Xiang Ren*, Miao Yu*, Inyoung Kim, Wonil Nam, Yuxiang Qin, Advanced microfluidics for synthetic biology and/or biomedical applications, Frontiers in Bioengineering and Biotechnology, 2024, 12, 1440206.
• Wenyu Gao, Inyoung Kim*, Wonil Nam, Xiang Ren, Wei Zhou, Masoud Agah, Nonparametric Bayesian functional clustering with applications to racial disparities in breast cancer. Statistical Analysis and Data Mining: The ASA Data Science Journal, 2024, 17(1), e11657.
• Xiang Ren, Ruyu Zhou, George Ronan, S. Gulberk Ozcebe, Jiaying Ji, Satyajyoti Senapati, Keith L. March, Eileen Handberg, David Anderson, Carl J. Pepine, Hsueh-Chia Chang, Fang Liu, Pinar Zorlutuna*, Towards Real-Time Myocardial Infarction Diagnosis: A Convergence of Machine Learning and Ion-Exchange Membrane Technologies Leveraging miRNA Signatures, Lab on a Chip, 2024, 24, 5203-5214.
• Muhammad Asraf Mansor, Chun Yang, Kar Lok Chong, Muhammad Asyraf Jamrus, Kewei Liu, Miao Yu, Mohd Ridzuan Ahmad*, Xiang Ren*, Label-free and Rapid Microfluidic Design Rules for Circulating Tumor Cell Enrichment and Isolation: A Review and Simulation Analysis, ACS Omega, 2025
• Xiang Ren, Qingwei Zhang, Kewei Liu, Ho-lung Li, Jack Zhou*, Modeling of Pneumatic Valve Dispenser for Printing Viscous Biomaterials in Additive Manufacturing, Rapid Prototyping Journal, 2014, Vol.20, Iss.6, pp. 434-443
• Xiang Ren, Kewei Liu, Qingwei Zhang, Hongseok (Moses) Noh, E.Caglan Kumbur, Wenqiao Wayne Yuan, Jack G. Zhou, Parkson Lee-Gau Chong*, Design, Fabrication and Characterization of Archaeal Tetraether Free-Standing Planar Membranes in a PDMS- and PCB-Based Fluidic Platform, ACS Applied Materials & Interfaces, 2014, Vol.6, No.15, pp. 12618-12628
• Yoontae Kim, Xiang Ren, Jin-Won Kim, Hongseok (Moses) Noh*, Direct inkjet printing of micro-scale silver electrodes on polydimethylsiloxane (PDMS) microchip, Journal of Micromechanics and Microengineering, 2014, Vol.24, Iss.11, pp. 115010
• Xiang Ren, Hao Lu, Jack G. Zhou, Parkson Lee-Gau Chong, Wenqiao Yuan, Moses Noh*, Porous Polydimethylsiloxane (PDMS) as a Gas-Liquid Interface for Microfluidic Applications, Journal of Microelectromechanical Systems, 2017, Vol.26, Iss.1, pp.120-126
• Xiang Ren, E. Caglan Kumbur, Jack G. Zhou, Moses Noh, Parkson Lee-Gau Chong*, Stability of Free-Standing Tetraether Planar Membranes in Microchips, Journal of Membrane Science, 2017, vol.540, pp.27-34
• Xiang Ren, Parham Ghassemi, Hesam Babahosseini, Jeannine S. Strobl, Masoud Agah*, Single-Cell Mechanical Characteristics Analyzed by Multi-Constriction Microfluidic Channels, ACS Sensors, 2017, vol.2, Iss.2, pp.290-299.
• Xiang Ren, Brittni M. Foster, Parham Ghassemi, Jeannine S. Strobl, Bethany A. Kerr, Masoud Agah*, Entrapment of Prostate Cancer Circulating Tumor Cells with a Sequential Size-Based Microfluidic Chip, Analytical Chemistry, 2018, vol.90, iss.12, pp.7526-7534
• Xiang Ren, Parham Ghassemi, Yasmine M. Kanaan, Tammey Naab, Robert L. Copeland, Robert L. Dewitty, Inyoung Kim, Jeannine S. Strobl, Masoud Agah*, Kernel-Based Microfluidic Constriction Assay for Tumor Sample Identification, ACS Sensors, 2018, vol.3, Iss.8, 1510-1521.
• Kruthika Kikkeri, Maria V. Riquelme Breazeal, Xiang Ren, Amy Pruden, Masoud Agah*, A Monolithic Dielectrophoresis Chip with Impedimetric Sensing for Assessment of Pathogen Viability, Journal of Microelectromechanical Systems, 2018, vol.27, iss.5, 810-817
• Xiang Ren, Parham Ghassemi, Jeannine S. Strobl, Masoud Agah*, Biophysical Phenotyping of Cells via Impedance Spectroscopy in Parallel Cyclic Deformability Channels, Biomicrofluidics, 2019, vol.13, 044103
• Wonil Nam, Xiang Ren, Seied Ali Safiabadi Tali, Parham Ghassemi, Inyoung Kim, Masoud Agah, Wei Zhou*, Refractive-Index-Insensitive Nanolaminated SERS Substrates for Label-free Raman Profiling and Classification of Living Cancer Cells, Nano Letters, 2019, vol.19, iss.10, 7273−7281
• Parham Ghassemi, Xiang Ren, Brittni M. Foster, Bethany A. Kerr, Masoud Agah*, Post-Enrichment Circulating Tumor Cell Detection and Enumeration via Deformability Impedance Cytometry, Biosensors and Bioelectronics, 2019, vol.150, 111868
• Xiang Ren, Wonil Nam, Parham Ghassemi, Jeannine S. Strobl, Inyoung Kim*, Wei Zhou*, Masoud Agah*, Scalable Nanolaminated SERS Multiwell Cell Culture Assay, Microsystems & Nano Engineering, 2020, vol.6, iss.47, doi: 10.1038/s41378-020-0145-3 [Featured Article]
• Gokhan Bahcecioglu, Gozde Basara, Bradley W. Ellis, Xiang Ren, Pinar Zorlutuna*, Breast cancer models: Engineering the tumor microenvironment, Acta Biomaterialia, 2020, vol.106, iss.1, 1-21.
• Parham Ghassemi, Koran S. Harris, Xiang Ren, Brittni M. Foster, Carl D. Langefeld, Bethany A. Kerr, Masoud Agah*, Comparative Study of Prostate Cancer Biophysical and Migratory Characteristics via Iterative Mechanoelectrical Properties (iMEP) and Standard Migration Assays, Sensors and Actuators B: Chemical, 2020, vol.321, 128522.
• Vivek Yadav, Nicholas Chong, Bradley Ellis, Xiang Ren, Satyajyoti Senapati, Hsueh-Chia Chang, Pinar Zorlutuna*, Constant-potential environment for activating and synchronizing cardiomyocytes colonies with on-chip ion-depleting perm-selective membranes, Lab on a Chip, 2020, vol. 20, iss.22, 4273-4284.
• Wonil Nam, Xiang Ren, Inyoung Kim, Jeannine Strobl, Masoud Agah, Wei Zhou*, Plasmonically Calibrated Label-free Surface-enhanced Raman Spectroscopy for Improved Multivariate Analysis of Living Cells in Cancer Subtyping and Drug Testing, Analytical Chemistry, 2021, vol.93, 4601-4610.
• Xiang Ren, Jorge Gomez, Mohammad Khairul Bashar, Jiaying Ji, Uryan Isik Can, Hsueh-Chia Chang, Nikhil Shukla, Suman Datta, Pinar Zorlutuna*, Cardiac muscle-cell-based coupled oscillator network for collective computing, Advanced Intelligent Systems, 2021, vol.4, iss.4, 2000253
• Gozde Basara, Mortaza Saeidi-Javash, Xiang Ren, Gokhan Bahcecioglu, Brian C. Wyatt, Babak Anasori, Yanliang Zhang, Pinar Zorlutuna*, Electrically conductive 3D printed Ti3C2Tx MXene-PEG composite constructs for tissue engineered human cardiac patches, Acta Biomaterialia, 2022, 139, 179-189.
• Xiang Ren, Bradley W. Ellis, George Ronan, Stuart Ryan Blood, Cameron DeShetler, Satyajyoti Senapati, Keith L. March, Eileen Handberg, David Anderson, Carl Pepine, Hsueh-Chia Chang, Pinar Zorlutuna*, A Multiplexed Ion-exchange Membrane-based miRNA (MIX.miR) Detection Platform for Rapid Diagnosis of Myocardial Infarction, Lab on a Chip, 2021, vol.21, iss.20, 3876-3887. [Back Cover]
• Jiaying Ji, Xiang Ren, Pinar Zorlutuna*, Cardiac cell patterning on customized microelectrode arrays for electrophysiological recordings, Micromachines, 2021, vol.12, iss.11, 1351.
• Bradley W. Ellis, George Ronan, Xiang Ren, Gokhan Bahcecioglu, Satyajyoti Senapati, David Anderson, Eileen Handberg, Keith L. March, Hsueh-Chia Chang, Pinar Zorlutuna*, Human Heart Anoxia and Reperfusion Tissue (HEART) model for the rapid study of exosome bound miRNA expression as biomarkers for myocardial infarction, Small, 2022, 2201330.
• Wonil Nam, Han Chen, Xiang Ren, Masoud Agah, Inyoung Kim, Wei Zhou*, Nanolaminate Plasmonic Substrates for High-Throughput Living Cell SERS Measurements and Artificial Neural Network Classification of Cellular Drug Responses, ACS Applied Nano Materials, 2022, vol.5, iss.8, 10358-10368.