lixin
School
School of Pharmaceutical Science and Technology
Professional Title
Associate professor
Discipline
Pharmaceutical Science
Contact Information
18710080407
lixin23@tju.edu.cn
B24_R417， 92 Weijin Road, Nankai District
300072
Research Interests
- Nucleic acid delivery system for therapeutic applications，Biomaterials，Nanomaterials for Immunoengineering
Academic Achievements
- Papers
- [1] 7. Jin, W., Li, X., Clergeaud, G., Ray, R. M., Hong Lin, M. K. T., Andresen, T. L., Gotfredsen, C. H., Nielsen, M., Astakhova, K., & Qvortrup, K. Small RNA stabilization via non-covalent binding with a metalloporphyrin nanocage to accomplish synergistic gene and photodynamic therapy. Cell Reports Physical Science, 2022, 3(12).
- [2] 6. Xin Li*, Sven Weller, Gael Clergeaud, Thomas L. Andresen*, A versatile method for conjugating lipid nanoparticles on T cells through combination of click chemistry and metabolic glycoengineering. Biotechnology Journal, 2024, 19(1): 2300339.
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- [3] 5. Xin Li, A-ning Sun, Yu-jie Liu, Wen-jie Zhang, Ning Pang, Shi-xuan Cheng, Xian-rong Qi. Amphiphilic dendrimer engineered nanocarrier systems for co-delivery of siRNA and paclitaxel to matrix metalloproteinase-rich tumors for synergistic therapy. NPG Asia Materials, 2018, 10: 238-254.
- [4] 4. Xin Li, Hólmfridur R Halldórsdóttir, Sven Weller, Anna Colliander, Martin Bak, Paul Kempen, Gael Clergeaud, Thomas L Andresen. Enhancing Adoptive Cell Therapy by T Cell Loading of SHP2 Inhibitor Nanocrystals before Infusion. ACS Nano, 2022, 16(7): 10918-10930.
- [5] 3. Fan, L., Du, P., Li, Y., Chen, X., Liu, F., Liu, Y., Petrov, A. M., Li, X. *, Wang, Z. *, & Zhao, Y. *. Targeted Liposomes Sensitize Plastic Melanoma to Ferroptosis via Senescence Induction and Coenzyme Depletion. ACS Nano, 2024,18(9): 7011–7023.
- [6] 2. Jin, W.#, Li, X.#, Argandona, S. M., Ray, R. M., Lin, M. K. T. H., Melle, F., Clergeaud, G., Lars Andresen, T., Nielsen, M., Fairen‐Jimenez, D., Astakhova, K., & Qvortrup, K. Surface engineering of metal-organic framework nanoparticles-based miRNA carrier: Boosting RNA stability, intracellular delivery and synergistic therapy. Journal of Colloid and Interface Science, 2025, 677: 429–440
- [7] 1. Luo, J., Shang, Y., Zhao, N., Lu, X., Wang, Z., Li, X.*, Meng, X.*, & Zhao, Y.*. Hypoxia-responsive micelles deprive cofactor of stearoyl-CoA desaturase-1 and sensitize ferroptotic ovarian cancer therapy. Biomaterials, 2025, 314.
- Honors & Awards
- [1] Wiley中国2024第一季度高贡献作者
- [2] 2024年度天津大学青年教工示范岗