主要从事纳米药物递送系统、药用高分子辅料的质谱分析技术开发和体内代谢动力学研究。近年来在Analytical Chemistry, Acta Pharmaceutica Sinica B, International Journal of Biological Macromolecules, Journal of Pharmaceutical Analysis, Talanta等期刊发表论文20余篇，主持国家自然科学基金青年科学基金项目1项，担任Chinese Chemical Letters, Journal of Analysis and Testing等期刊青年编委；中国医药生物技术协会药物分析技术分会委员、中国医药质量管理协会“临床研究质量与评价专业委员会”委员。

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• X. Xu, H. Yang, J. Chi, H. Sun, X. Meng, J. Gu, Pharmacokinetics, tissue distribution and metabolism of hydroxyethyl starch 130/0.4 in rats, Int J Biol Macromol, 309 (2025) 142684.
• X. Meng, J. Yao, J. Gu, Advanced bioanalytical techniques for pharmacokinetic studies of nanocarrier drug delivery systems, J Pharm Anal, 15 (2025) 101070.
• X. Meng, C. Su, Z. Zhang, Y. Li, Y. Zhang, J. Li, L. Gan, J. Gu, Overcoming the challenge of potent endogenous interferences in limaprost quantification: An innovative methodology combining differential mobility spectrometry with LC-MS/MS for ultra-high sensitivity, selectivity and significantly enhanced throughput, Talanta, 277 (2024) 126411.
• Y. Liu, X. Meng, Y. Zhang, L. Zhang, Y. Shan, J. Gu, D. Sun, High-throughput bioanalysis of sitagliptin in plasma using direct analysis in real time mass spectrometry and its application in the pharmacokinetic study thereof, J Sep Sci, 45 (2022) 631-637.
• N. Xiao, M. Nie, H. Pang, B. Wang, J. Hu, X. Meng, K. Li, X. Ran, Q. Long, H. Deng, N. Chen, S. Li, N. Tang, A. Huang, Z. Hu, Integrated cytokine and metabolite analysis reveals immunometabolic reprogramming in COVID-19 patients with therapeutic implications, Nat Commun, 12 (2021) 1618.
• X. Meng, Z. Zhang, J. Tong, H. Sun, J.P. Fawcett, J. Gu, The biological fate of the polymer nanocarrier material monomethoxy poly(ethylene glycol)-block-poly(d,l-lactic acid) in rat, Acta Pharm Sin B, 11 (2021) 1003-1009.
• X. Meng, H. Pang, F. Sun, X. Jin, B. Wang, K. Yao, L. Yao, L. Wang, Z. Hu, Simultaneous 3-Nitrophenylhydrazine Derivatization Strategy of Carbonyl, Carboxyl and Phosphoryl Submetabolome for LC-MS/MS-Based Targeted Metabolomics with Improved Sensitivity and Coverage, Anal Chem, 93 (2021) 10075-10083.
• D. Sun, X. Meng, T. Ren, J.P. Fawcett, H. Wang, J. Gu, Establishment of a Charge Reversal Derivatization Strategy to Improve the Ionization Efficiency of Limaprost and Investigation of the Fragmentation Patterns of Limaprost Derivatives Via Exclusive Neutral Loss and Survival Yield Method, J Am Soc Mass Spectrom, 29 (2018) 1365-1375.
• X. Zhou, X. Meng, L. Cheng, C. Su, Y. Sun, L. Sun, Z. Tang, J.P. Fawcett, Y. Yang, J. Gu, Development and Application of an MS(ALL)-Based Approach for the Quantitative Analysis of Linear Polyethylene Glycols in Rat Plasma by Liquid Chromatography Triple-Quadrupole/Time-of-Flight Mass Spectrometry, Anal Chem, 89 (2017) 5193-5200.
• X. Meng, H. Xu, Z. Zhang, J.P. Fawcett, J. Li, Y. Yang, J. Gu, Differential mobility spectrometry tandem mass spectrometry with multiple ion monitoring for the bioanalysis of liraglutide, Anal Bioanal Chem, 409 (2017) 4885-4891.
• X. Meng, B. Yang, J. Gao, W. Peng, H. Wang, M. Shi, R. Mortishire-Smith, Y. Yang, J. Gu, Simultaneous quantitation of two diastereoisomers of lobaplatin in rat plasma by supercritical fluid chromatography with tandem mass spectrometry and its application to a pharmacokinetic study, J Sep Sci, 38 (2015) 3803-3809.