天津大学教师个人主页系统 Li Junjie 首页中文主页

教育经历

· 2004.9 - 2007.3

Tianjin University - Materials Science - 硕士
· 2007.9 - 2010.6

Tianjin University - Chemical Engineering - 博士

研究方向

· Biomedical Materials
· Polymer Chemistry
· Cardiac and bone tissue engineering
· Hemostatic first aid materials
· Flexible sensor

个人简介

Junjie Li is currently the Professor of Material Chemical Engineering at Tianjin University, Tianjin. He received his Ph.D degree in 2010 from Tianjin University under the guidance of Profs. Fanglian Yao and Kangde Yao in Materials Science. He was a postdoctoral fellow at the Academy of Military Medical Sciences (Beijing), with Prof. Changyong Wang between 2010 and 2012. Now, he is the director of Tianjin University-Wenzhou Biomaterials Innovation Center. His current research interests focus on biomaterials, surface modification, tissue engineering and flexible sensor.

学术成果

论文成果

[1]Zhihui Qin, Xia Sun, Haitao Zhang Qingyu Yu, Xueyuan Wang, Shaoshuai He, Fanglian Yao*, Junjie Li.* A transparent, ultrastretchable and fully recyclable gelatin organohydrogel based electronic sensor with broad operating temperature. Journal of Materials Chemistry A, 2020,8, 4447-4456
[2]Xiaojun Wu, Hong Sun, Zhihui Qin, Pengcheng Che, Xue Yi, Qingyu Yu, Haitao Zhang, Xia Sun, Fanglian Yao, Junjie Li. Fully physically crosslinked pectin-based hydrogel with high stretchability and toughness for biomedical application. International Journal of Biological Macromolecules, 2020, 149, 707-716.
[3]Zhihui Qin, Xia Sun, ,Qingyu Yu Haitao Zhang, Xiaojun Wu, Mengmeng Yao, Wenwen Liu, Fanglian Yao,* Junjie Li.* Carbon Nanotubes/Hydrophobically Associated Hydrogels as Ultrastretchable, Highly Sensitive, Stable Strain, and Pressure Sensors. ACS Applied Materials & Interfaces 2020, 12, 4, 4944-4953
[4]Wenwen Liu, Junjie Li*, Zhihui Qin, Mengmeng Yao, Xinlu Tian, Zhiming Zhang, Li Zhang, Qin Guo, Linhua Zhang, Dunwan Zhu*, Fanglian Yao*. Zwitterionic Unimolecular Micelles with pH and Temperature Response: Enhanced In Vivo Circulation Stability and Tumor Therapeutic Efficiency. Langmuir, doi.org/10.1021/acs.langmuir.0c00206
[5]Xia Sun, Zhihui Qin, Lei Ye, Haitao Zhang, Qingyu Yu, Xiaojun Wu, Junjie Li*, Fanglian Yao*. Carbon Nanotubes Reinforced Hydrogel as Flexible Strain Sensor with High Stretchability and Mechanically Toughness. Chemical Engineering Journal 2020, 382, 122832.
[6]Honglin Luo, Deqiang Gan, Miguel Gama, Junpin Tu, Fanglian Yao, Quanchao Zhang, Haiyong Ao, Zhiwei Yang, Junjie Li, Yizao Wan. Interpenetrated nano- and submicro-fibrous biomimetic scaffolds towards enhanced mechanical and biological performances. Materials Science & Engineering C 2020, 108, 110416.
[7]Zhihui Qin, Dianyu Dong, Mengmeng Yao, Qingyu Yu, Xia Sun, Qi Guo, Haitao Zhang, Fanglian Yao, Junjie Li*. Freezing-Tolerant Supramolecular Organohydrogel with High Toughness, Thermoplasticity, and Healable and Adhesive Properties. ACS Appl. Mater. Interfaces 2019, 11, 21184−21193
[8]Yao Shu, Yu Zhou, Pengwei Ma, Chunge Li, Cheng Ge, Ying Wang, Qihong Li, Kaitao Yu, Rongjian Lu, Xuan Zou, Yuji Yin, Junjie Li*. Degradation in vitro and in vivo of β-TCP/MCPM-based premixed calcium phosphate cement. Journal of the Mechanical Behavior of Biomedical Materials, 2019, 90, 86-95.
[9]Dianyu Dong, Tong Hao, Changyong Wang, Ying Zhang, Zhihui Qin, Boguang Yang, Wancai Fang, Lei Ye, Fanglian Yao,* Junjie Li*. Zwitterionic starch-based hydrogel for the expansion and “stemness” maintenance of brown adipose derived stem cells. Biomaterials, 2018, 157, 149-160.
[10]Ershuai Zhang, Qi Guo, Feng Ji, Xinlu Tian, Jing Cui, Yihang Song, Hong Sun, Junjie Li*, Fanglian Yao*. Thermoresponsive Polysaccharide-based Composite Hydrogel with Antibacterial and Healing-promoting Activities for Preventing Recurrent Adhesion after Adhesiolysis. Acta Biomaterialia, 2018, 74, 439-453.
[11]Meng Xu, Feng Ji, Zhihui Qin, Dianyu Dong, Xinlu Tian, Rui Niu, Da Sun, Fanglian Yao*, Junjie Li*. Biomimetic mineralization of Hydroxyapatite Crystal in the Presence of Zwitterionic Polymer. CrystEngComm, 2018, 20, 2374–2383
[12]Zhihui Qin, Rui Niu, Chenjue Tang, Jun Xia, Feng Ji, Dianyu Dong, Haitao Zhang, Shuo Zhang, Junjie Li*, Fanglian Yao*. A Dual-Crosslinked Strategy to Construct Physical Hydrogels with High Strength, Toughness, Good Mechanical Recoverability, and Shape-Memory Ability. Macromolecular Materials Science and Engineering, 2018, 303, 1700396.
[13]Rui Niu, Zhihui Qin, Feng Ji, Meng Xu, Xinlu Tian, Junjie Li,* Fanglian Yao*.Hybrid pectin-Fe3+/polyacrylamide double network hydrogel with excellent strength, high stiffness, superior toughness and notch-insensitivity. Soft Matter, 2017, 13, 9237—9245.
[14]Feng Ji, Junjie Li*, Zhihui Qin, Boguang Yang, Ershuai Zhang, Dianyu Dong, Jinmei Wang, Yan Wen, Liang Tian, Fanglian Yao*. Engineering pectin-based hollow nanocapsules for delivery of anticancer drug. Carbohydrate Polymers, 2017, 177, 86–96.
[15]Tong Hao, Junjie Li*, Fanglian Yao, Dianyu Dong, Yan Wang, Boguang Yang, Changyong Wang*. Injectable Fullerenol/Alginate Hydrogel for Suppression of Oxidative Stress Damage in Brown Adipose-Derived Stem Cells and Cardiac Repair. ACS Nano, 2017, 11, 5474−5488.
[16]Yuhang Zhou, Junjie Li*, Ying Zhang, Dianyu Dong, Ershuai Zhang, Feng Ji, Zhihui Qin, Jun Yang, and Fanglian Yao*. Establishment of a Physical Model for Solute Diffusion in Hydrogel: Understanding the Diffusion of Proteins in Poly (Sulfobetaine Methacrylate) Hydrogel. The Journal of Physical Chemistry B, 2017, 121, 800-814.
[17]Yan Wen, Fan Li, Chunge Li, Yuji Yin*, Junjie Li*. High mechanical strength chitosan based hydrogels cross-linked by poly(ethylene glycol)/polycaprolactone micelles for controlled release of drug/growth factor. Journal of Materials Chemistry B, 2017, 5, 961-971.
[18]Yabin Zhang, Lei Ye, Jing Cui, Boguang Yang, Hong Sun, Junjie Li*, Fanglian Yao*. A Biomimetic Poly(vinyl alcohol)−Carrageenan Composite Scaffold with Oriented Microarchitecture. ACS Biomaterials Science and Engineering. 2016, 2, 544−557.
[19]Chunge Li, Yufeng Qian, Shuang Zhao, Yuji Yin, Junjie Li*. Alginate/PEG based microcarriers with cleavable crosslinkage for expansion and non-invasive harvest of human umbilical cord blood mesenchymal stem cells. Materials Science and Engineering C. 2016, 64: 43–53
[20]Wancai Fang, Hong Zhang, Jianwei Yin, Boguang Yang, Yabin Zhang, Junjie Li*, Fanglian Yao*. Hydroxyapatite Crystal Formation in the Presence of Polysaccharide. Crystal Growth and Design. 2016, 16, 1247−1255.
[21]Yan Wang, Lina Li, Junjie Li*, Boguang Yang, Changyong Wang, Wancai Fang, Feng Ji, Yan Wen, Fanglian Yao. A stable and pH-responsive polyamidoamine based unimolecular micelles capped with zwitterionic polymer shell for anticancer drug delivery. RSC Advances, 2016, 6, 17728-17739.
[22]Tong Hao, Jin Zhou, Shuanghong Lü, Boguang Yang, Yan Wang, Wancai Fang, Xiaoxia Jiang, Qiuxia Lin, Junjie Li*, Changyong Wang*. Fullerene Mediates Proliferation and Cardiomyogenic Differentiation of Adipose-Derived Stem Cells via Modulation of MAPK Pathway and Cardiac Protein Expression. International Journal of Nanomedicine, 2016, 11: 269-283
[23]Boguang Yang, Fanglian Yao, Tong Hao, Wancai Fang, Lei Ye, Yabin Zhang, Yan Wang, Junjie Li*, Changyong Wang*. Development of Electrically Conductive Double-Network Hydrogels via One-Step Facile Strategy for Cardiac Tissue Engineering. Advanced Healthcare Materials, 2016, 4, 474-488.
[24]Boguang Yang, Changyong Wang, Yabin Zhang, Lei Ye, Yufeng Qian, Yao Shu, Jinmei Wang, Junjie Li*, Fanglian Yao*. Thermoresponsive Poly (N-Vinylcaprolactam-co-Sulfobetaine Methacrylate) Zwitterionic Hydrogel Exhibiting Switchable Anti-Biofouling and Cytocompatibility. Polymer Chemistry, 2015, 6, 3431-3442.
[25]Yao Shu, Tong Hao, Fanglian Yao, Yufeng Qian, Yan Wang, Boguang Yang, Junjie Li*, Changyong Wang*. RoY Peptide Modified Chitosan Based Hydrogel to Improve Angiogenesis and Cardiac Repair under Hypoxia. ACS Applied Materials & Interfaces, 2015, 7, 6505−6517.
[26]Junjie Li*, Shuangzhuang Guo, Min Wang, Lei Ye, Fanglian Yao*. Poly (lactic acid)/Poly (ethylene glycol) Block Copolymer Based Shell or Core Cross-linked Micelles for Controlled Release of Hydrophobic Drug. RSC Advances, 2015, 5, 19484–19492.
[27]Junjie Li, Boguang Yang, Yufeng Qian, Qiyu Wang, Ruijin Han, Tong Hao, Yao Shu, Yabin Zhang, Fanglian Yao, Changyong Wang. Iota-carrageenan/chitosan/gelatin scaffold for the osteogenic differentiation of adipose-derived MSCs in vitro. J Biomed Mater Res: Part B- Appl Biomater, 2015:103B:1498–1510.
[28]Chunge Li, Shuan Zhao, Yanyan Zhao, Junjie Li*, Yuji Yin*. Chemically Crosslinked Alginate Porous Microcarriers Modified with Bioactive Molecule for Expansion of Human Hepatocellular Carcinoma. J Biomed Mater Res: Part B- Appl Biomater, 2014, 102B: 1648–1658.
[29]Junjie Li, Yao Shu, Tong Hao, Yan Wang, Yufeng Qian, Cuimi Duan, Hongyu Sun, Qiuxia Lin, Changyong Wang. A chitosaneglutathione based injectable hydrogel for suppression of oxidative stress damage in cardiomyocytes. Biomaterials 2013, 34: 9071-9081.
[30]Junjie Li, YiPing Chen, Yin YJ, Yao FL, Kangde Yao. Modulation of nano-hydroxyapatite size via formation on chitosan-gelatin network film in situ. Biomaterials, 2007, 28:781-790.
[31]Junjie Li, Yin YJ, Yao FL, Zhang LL, Yao KD. Effect of nano- and micro-hydroxyapatite/chitosan-gelatin network film for human gastric cancer cells. Materials Letters, 2008, 62: 3220-3223.
[32]Junjie Li, Yan Dou, Jun Yang，Hong Zhang，Fanglian Yao, Haibing Wang, Kangde Yao. Surface characterization and Biocompatibility of Micro- and Nano-hydroxyapatite/chitosan-gelatin Network Films. Materials Science and Engineering C 2009, 29:1207-1215.
[33]Junjie Li, Dunwan Zhu, Fanglian Yao, Kangde Yao, Formation of nano-hydroxyapatite crystal in situ in chitosan-pectin polyelectrolyte complex system. Materials Science and Engineering C 2010, 30: 795–803.
[34]Junjie Li, Hong Sun, Rui Zhang, Ruyue Li, Yuji Yin, Hui Wang, Yuxi Liu, Fanglian Yao, Kangde Yao. Modulation of mesenchymal stem cells behaviors by chitosan/gelatin/pectin network film. J Biomed Mater Res: Part B- Appl Biomater 2010, 95B: 308-319.
[35]Junjie Li, Hong Sun, Chao Ma, Yuli Yao, Fanglian Yao, Kangde Yao. Biomimetic multicomponent polysaccharide/nano-hydroxyapatite composites for bone tissue engineering. Carbohydrate Polymers 2011, 85:885-894.
[36]Lisheng Zhao, Junjie Li (co-first author), Liang Zhang, Yu Wang, Jiexin Wang, Bin Gu, Jianfeng Chen, Tong Hao, Changyong Wang*, Ning Wen*. Preparation and characterization of calcium phosphate/pectin scaffolds for bone tissue engineering. RSC Advances, 2016, 6, 62071–62082.
[37]Yongchao Mou, Yan Wang, Junjie Li (co-first author), Shuanghong Lv, Cuimi Duan, Zhiyan Du, Guili Yang, Weizhen Chen, Siyang Zhao, Jin Zhou, Changyong Wang. Immunohistochemical characterization and functional identification of mammary gland telocytes in the self-assembly of reconstituted breast cancer tissue in vitro. J Cell Mol Med 2013, 17: 65-75.

著作成果

[1]李俊杰，姚康德。组织工程用生物材料，《今日化学》。高等教育出版社。2013. (ISBN:978-7-04-037000-3).
[2]李俊杰，姚芳莲。陶瓷、玻璃及玻璃-陶瓷，《生物医用材料：医用材料导论》，科学出版社, 2011. (ISBN: 978-7-030990-7).
[3]Kangde Yao, Fanglian Yao, Junjie Li，Yuji Yin. Chitosan based Gel. In “Smart Materials”, CRC Press USA 2008 (ISBN: 978-1-4200-4372-3).
[4]Junjie Li, Yuxi Liu, Fanglian Yao. Polymer Matrix Mediated Synthesis of Nano Hydroxyapatite Crystals. In “Hydroxyapatite: Synthesis, Properties and Applications”. NOVA publishers, 2012 (ISBN:978-1-62081-934-0).
[5]Kangde Yao, Junjie Li, Fanglian Yao, Yuji Yin. Chitosan based Hydrogels: Function and Application. CRC Press, USA, 2011. (ISBN: 978-1-4398-2114-5).

Li Junjie