School of Life Sciences
Professor
18002007081
022-27403888
wenhai.xiao@tju.edu.cn
Room B902,Tiannan Building, Tianjin Univeristy, Weijin Road, Nankai District, Tianjin
Dr. Wenhai Xiao is an associated professor in the School of Chemical Engineering & Technology at Tianjin University. He received his B.S. degree and Ph.D. degree in Pharmaceutical Engineering from Tianjin University in China in 2004 and 2010, respectively. Dr. Xiao has authored and co-authored over 15 research articles and over 10 patents. He focused on heterologous production of natural products in microbial cell factories by metabolic engineering and synthetic biology, which has been published in top journal, such as science, PNAS, Metabolich Engineering et al. To date, total citations has exceed 700.
- Visiting student| Massachusetts Institute of Technology, US| Chemical Engineering| 2010
- Doctor| Tianjin University| Pharmaceutical Engineering| 2010
- Bachelor| Tianjin University| Pharmaceutical Engineering| 2004
- microbial production of natural products by metabolic engineering and synthetic biology
- synergy between metabolic engineering and protein engineering
- Member of Specialized Committee of Pharmaceutical Engineering Society of Chinese Pharmaceutical Association
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2017.6-2019.12
 School of Chemical Engineering and Technology, Tianjin University | associated professor  -
2015.1-2017.6
 SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin University | Professor  -
2012.10-2014.12
 Manus Biosynthesis. Inc, Boston, US | Senior Scientist  -
2011.1-2012.9
 CABIO Biotech(Wuhan) Co., Ltd | Engineer in-Chief of Bioprocess 
- Papers
- [1] Isoprenoid Pathway Optimization for Taxol Precursor Overproduction in Escherichia coli
- [2] Combining metabolic and protein engineering of a terpenoid biosynthetic pathway for overproduction and selectivity control
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- [3] Rational, combinatorial, and genomic approaches for engineering L-tyrosine production in Escherichia coli
- [4] Biosynthesis of odd-chain fatty alcohols in Escherichia coli
- [5] Bug mapping and fitness testing of chemically synthesized chromosome X
- [6] Lycopene overproduction in Saccharomyces cerevisiae through combining pathway engineering with host engineering
- [7] Engineering of β-carotene hydroxylase and ketolase for astaxanthin overproduction in Saccharomyces cerevisiae
- [8] Heterologous biosynthesis and manipulation of crocetin in Saccharomyces cerevisiae
- [9] Improved campesterol production in engineered Yarrowia lipolytica strains
- [10] Manipulation of GES and ERG20 for geraniol overproduction in Saccharomyces cerevisiae
- [11] Cell foundry with high product specificity and catalytic activity for 21-deoxycortisol biotransformation
- [12] Spatial-temporal distribution of nitric oxide involved in regulation of phenylalanine ammonialyase activation and Taxol production in immobilized Taxus cuspidata cells
- [13] Alleviating Redox Imbalance Enhances 7-Dehydrocholesterol Production in Engineered Saccharomyces cerevisiae
- [14] 化学品绿色制造核心技术合成生物学
- [15] Engineering Yarrowia lipolytica for Campesterol Overproduction
- [16] 如何工程化生物学
- [17] Heterologous biosynthesis and manipulation of alkanes in Escherichia
- Patents
- [1] A recombinant yeast strain and related construction method and application
- [2] Engineering strain, construction method and application in producing saffron acid
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- [3] Recombinant plasmid and recombinant yeast strain as well as construction method and application
- [4] A recombinant yeast strain and related construction method and application
- [5] A recombinant yeast strain and related construction method and application
- [6] A recombinant yeast strain and related construction method and application
- [7] Application of acetyl co-enzyme A enhancement module in enhancing synthesis of 7- cholesterol dehydrogenase in microorganism
- [8] Application of cofactor regeneration modules in enhancing synthesis of secondary metabolites in microorganisms
- [9] construction of a recombinant lipolytic yeast strain and its application
- [10] Gene and application, gene parts, biosynthesis of odd middle length fatty acohol and even alkane