肖文海
- 教师名称：肖文海
- 教师拼音名称：Xiao Wenhai
- 出生日期：1982-01-12
- 性别：男
- 职称：教授
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基本信息
研究方向
获奖情况
论文成果
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Dr. Wenhai Xiao is an associated professor in the School of Chemical Engineering & Technology at Tianjin University. He received his B.S. degree and Ph.D. degree in Pharmaceutical Engineering from Tianjin University in China in 2004 and 2010, respectively. Dr. Xiao has authored and co-authored over 15 research articles and over 10 patents. He focused on heterologous production of natural products in microbial cell factories by metabolic engineering and synthetic biology, which has been published in top journal, such as science, PNAS, Metabolich Engineering et al. To date, total citations has exceed 700.
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- Ajikumar PK.Isoprenoid Pathway Optimization for Taxol Precursor Overproduction in Escherichia coli.Science.2010
- Leonard E, Ajikumar PK.Combining metabolic and protein engineering of a terpenoid biosynthetic pathway for overproduction and selectivity control.Proc Natl Acad Sc....2010
- Santos CN.Rational, combinatorial, and genomic approaches for engineering L-tyrosine production in Escherichia coli.Proc Natl Acad Sc....2012
- Cao YX.Biosynthesis of odd-chain fatty alcohols in Escherichia coli.Metab Eng.2015
- Wu Y, Li BZ.Bug mapping and fitness testing of chemically synthesized chromosome X.Science.2017
- Chen Y.Lycopene overproduction in Saccharomyces cerevisiae through combining pathway engineering with host engineering.Microb Cell Fact.2016
- Wang R, Gu X.Engineering of β-carotene hydroxylase and ketolase for astaxanthin overproduction in Saccharomyces cerevisiae.FRONT CHEM SCI EN....2015
- Chai F, Wang Y, Mei X.Heterologous biosynthesis and manipulation of crocetin in Saccharomyces cerevisiae.Microb Cell Fact.2017
- Zhang Y, Wang Y.Improved campesterol production in engineered Yarrowia lipolytica strains.Biotechnol Lett.2017
- Jiang GZ, Yao MD.Manipulation of GES and ERG20 for geraniol overproduction in Saccharomyces cerevisiae.Metab Eng.2017
- Xiong S, Wang Y.Cell foundry with high product specificity and catalytic activity for 21-deoxycortisol biotransformation.Microb Cell Fact.2017
- Xiao WH.Spatial-temporal distribution of nitric oxide involved in regulation of phenylalanine ammonialyase activation and Taxol production in immobilized Taxus cuspidata cells.J Biotechnol.2019
- Su W.Alleviating Redox Imbalance Enhances 7-Dehydrocholesterol Production in Engineered Saccharomyces cerevisiae.PLoS One.2019
- 肖文海.化学品绿色制造核心技术合成生物学.化工学报.2019
- Du HX, Xiao WH, Wang Y.Engineering Yarrowia lipolytica for Campesterol Overproduction.PLoS One.2019
- 肖文海.如何工程化生物学.化工进展.2019
- Cao YX，Xiao WH.Heterologous biosynthesis and manipulation of alkanes in Escherichia.Metab Eng.2019
教育经历
- 2008.10-2010.5 Massachusetts Institute of Technology, US Chemical Engineering Visiting student
- 2004.9-2010.12 Tianjin University Pharmaceutical Engineering Doctor
- 2000.9-2004.6 Tianjin University Pharmaceutical Engineering Bachelor
工作经历
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2017.6 -2019.12
|School of Chemical Engineering and Technology, Tianjin University|associated professor
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2015.1 -2017.6
|SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin University|Professor
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2012.10 -2014.12
|Manus Biosynthesis. Inc, Boston, US|Senior Scientist
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2011.1 -2012.9
|CABIO Biotech(Wuhan) Co., Ltd|Engineer in-Chief of Bioprocess
专利成果
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A recombinant yeast strain and related construction method and application
2017
9
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Engineering strain, construction method and application in producing saffron acid
2017
9
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Recombinant plasmid and recombinant yeast strain as well as construction method and application
2017
9
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A recombinant yeast strain and related construction method and application
2017
9