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Matthias Bureik
- 教师拼音名称：Matthias Bureik
- 性别：男
- 职称：教授
- 所属院系：药物科学与技术学院
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· Neunzig I., C.-A. Dragan, M. Widjaja, A.E. Schwaninger, F.T. Peters, H.H. Maurer & M. Bureik (2011) Whole-cell Biotransformation Assay for Investigation of the Human Drug Metabolizing Enzyme CYP3A7. Biochim Biophys Acta 1814, 161-167.
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· Dragan C.-A., F.T. Peters, P. Bour, A.E. Schwaninger, S.M. Schaan, I. Neunzig, M. Widjaja, J. Zapp, T. Kraemer, H.H. Maurer & M. Bureik (2011) Convenient Gram-Scale Metabolite Synthesis by Engineered Fission Yeast Strains Expressing Functional Human P450 Systems. Appl Biochem Biotechnol 163, 965-980.
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· Naumann J.M., A. Zöllner, C.-A. Dragan, J. Messinger, J. Adam & M. Bureik (2011) Biotechnological production of 20α-dihydrodydrogesterone at pilot scale. Appl Biochem Biotechnol 165, 190-203.
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· Buchheit D., E.I. Schmitt, D. Bischoff, T. Ebner & M. Bureik (2011) S-Glucuronidation of 7-mercapto-4-methylcoumarin by human UDP glycosyltransferases in genetically engineered fission yeast cells. Biol Chem 392, 1089-95.
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· Parr, M.K., A. Zöllner, G. Fusshöller, G. Opfermann, N. Schlörer, M. Zorio, M. Bureik & W. Schänzer (2012) Unexpected contribution of cytochrome P450 enzymes CYP11B2 and CYP21, as well as CYP3A4 in xenobiotic androgen elimination - Insights from metandienone metabolism. Toxicol Lett. 213, 381-391.
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· Neunzig, I., M. Widjaja, F.T. Peters, H.H. Maurer, A. Hehn, F. Bourgaud & M. Bureik (2013) Coexpression of CPR from various origins enhances biotransformation activity of human CYPs in S. pombe. Appl Biochem Biotechnol. 170, 1751-1766.
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· Klein, T., S. Lange, N. Wilhelm, M. Bureik, T.H. Yang, E. Heinzle & K. Schneider (2014) Overcoming the metabolic burden of protein secretion in Schizosaccharomyces pombe - A quantitative approach using C-13-based metabolic flux analysis. Metab Eng. 21, 34-45.
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· Weyler C, M. Bureik & E. Heinzle (in press) Selective oxidation of UDP-glucose to UDP-glucuronic acid using permeabilized Schizosaccharomyces pombe expressing human UDP-glucose 6-dehydrogenase. Biotechnol Lett.
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· Neunzig, I.; Göhring, A.; Dragan, C.-A.; Zapp, J.; Peters, F. T.; Maurer, H. H.; Bureik, M. Production and NMR analysis of the human ibuprofen metabolite 3-hydroxyibuprofen. 2012, J. Biotechnol. 157, 417.
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· Neunzig, I.; Widjaja, M.; Dragan, C.-A.; Peters, F. T.; Maurer, H. H.; Bureik, M. Engineering of human CYP3A enzymes by combination of activating polymorphic variants. Appl. Biochem. Biotechnol. 2012, 168, 785.
