教育经历
· 1999.9 - 2003.7
Fudan University - Life Sciences - Bachelor of Science
· 2003.9 - 2009.10
McMaster University - Biochemistry and Biomedical Sciences - Ph. D.
工作经历
· 2021.6 - 2025.8
Tianjin University → Professor
· 2016.9 - 2021.5
Tianjin University → Associate Professor
· 2010.6 - 2016.8
University of British Columbia → Research Associate
· 2009.10 - 2010.6
Cold Spring Harbor Laboratory → Postdoctoral Fellow
研究方向
· Unraveling the structure-function mechanisms of human and insect ion channels using cryo-electron microscopy, protein crystallography, and integrative biophysical/physiological approaches to drive therapeutic and insecticide discovery.
授课信息
社会兼职
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· Current Pharmaceutical Design 客座编辑
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· Frontiers in Insect Science客座编辑
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· Cancer Biology and Medicine编委
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· Frontiers in Physiology客座编辑
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· Agriculture 客座编辑
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· Advanced Agrochem青年编委
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· 农药学学报青年编委
个人简介
Lab website: www.yuchilab.com
天津大学教授，博导，国家优青。复旦大学本科，加拿大麦克马斯特大学博士，纽约冷泉港实验室博士后，加拿大英属哥伦比亚大学副研究员，2016年加入天津大学药学院。专注于离子通道靶标蛋白的结构功能研究，以及相关的疾病机理和药物高通量筛选开发工作。至今已在国际主流期刊Nature、Nature Chemical Biology、Nature Communications、Molecular Cell、PNAS、eLife、JACS、ACS Catalysis、BMC Biology等发表论文八十余篇，申请多项专利，作为项目负责人承担了科技部重点研发、国家优秀青年基金等多个国家级项目，担任亚太生理学会、中国化学会、中国生物物理学会细胞钙信号、中国抗癌协会肿瘤疫苗等专业委员会的委员，及Cancer Biology & Medicine、Current Pharmaceutical Design、Advanced Agrochem等期刊编委，和Nature Chemical Biology、Nature Communications、eLife、ACS Catalysis等多个杂志的特约审稿人。获中国化学会中化扬农农业化学创新奖、迈克尔约翰佩琪青年科学家奖、迈克尔史密斯奖、美国化学会优秀指导教师奖等荣誉称号。
学术成果
论文成果
专利成果
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[1]The application of compounds in the inhibition of insecticide resistance
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[4]The application of the compound as an inhibitor of acetylcholinesterase
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[7]The application of compounds in the control of pests and the synergistic enhancement of pesticides
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[8]A protein purification method based on the properties of calmodulin
奖励与荣誉
1. The Best Mentor Award of the Beijing-Tianjin-Hebei Branch of the American Chemical Society
2. The recipient of the Youth Project of the Tianjin Talent Program
3. Tianjin City Award for Outstanding Graduation Thesis Supervisors for Undergraduate Students
6. Tianjin University Outstanding Doctoral Dissertation Supervisor Award
7. The instructor of the winner of the Bronze Award in the Tianjin University Internet Plus Competition
8. Tianjin University Outstanding Master's Thesis Supervisor Award
团队
Yuchi Lab
Manager: Jing Xie
Postdoctoral Researchers: Raja, Zhiyan Wang, Wenjuan Li
PhD Students: Chen Liu, Heng Jiang, Zhiyuan Hao, Yongliang Zhang, Hadiatullah, Wenlan Wang, Chuli Song, Peizhuo Li, Yuanzhuang Xu, Junheng Li, Zuwei Qu, Cailing Tang, Ye Liu, Romisa Mamoun, Qing Wang, Xiang Li
Master Srudents: Runqi Jin, Yilong Li, Xinjing Peng, Wenxiu Chang, Ning Yang, Qi Feng, Hanmeng Liu