
尉迟之光
- 教师拼音名称:Michael Yuchi
- 出生日期:1982-02-25
- 职务:Vice Dean
- 性别:男
- 职称:教授
- 所属院系:药物科学与技术学院
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Hadiatullah, H.; Lin, L.; Wang, Z.; Sundarraj, R.; Wang, Q.; Lai, X.; Kurebayashi, N.; Kobayashi, T.; Yamazawa, T.; Chen, Y. S.; et al. Crystal structures of Ryanodine Receptor reveal dantrolene and azumolene interactions guiding inhibitor development. Nature Communications 2025, 16 (1), 10110. DOI: 10.1038/s41467-025-65096-1.
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Cui, X., Zheng, Y., Liu, Y., Yuchi, Z.*, Yuan, Y.* AI-driven de novo enzyme design: Strategies, applications, and future prospects. Biotechnol Adv.2025, doi: 10.1016/j.biotechadv.2025.108603.
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Lin, L., Wang, C., Wang, W., Jiang, H., Murayama, T., Kobayashi, T., Hadiatullah, H., Chen, Y. S., Wu, S., Wang, Y., Korza, H., Gu, Y., Zhang, Y., Du, J., Van Petegem, F.*, and Yuchi, Z.* Cryo-EM structures of ryanodine receptors and diamide insecticides reveal the mechanisms of selectivity and resistance. Nature Communications. 2024, 15: 9056
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Chen, W., Cao, P., Liu, Y., Yu, A., Wang, D., Chen, L., Sundarraj, R., Yuchi, Z., Gong, Y.*, Merzendorfer, H.*, Yang Q.* Structural basis for directional chitin biosynthesis. Nature. 2022, 61: 402-408.
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Duan, Y., Wei, Y., Xing, M., Liu, J., Jiang, L., Lu, Q., Liu, X., Liu, Y., Ang, EL., Liao, RZ., Yuchi, Z.*, Zhao, H.*, Zhang, Y.* Anaerobic hydroxproline degradation involving c-n cleavage by a glycyl radical enzyme. Journal of the American Chemical Society, 2022, 144(22): 9715-9722.
著作成果
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Nayak, BC., and Yuchi, Z. (2018) Calmodulin-based recombinant protein purification strategies, Calmodulin: Structure, Mechanisms and Functions, Nova Science Publishers
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Yuchi, Z., Kimlicka, L., and Van Petegem, F. (2013) Structural insights into disease mutations of the Ryanodine Receptor. Genetic Disorders, Intech