尉迟之光
- 教师拼音名称：Michael Yuchi
- 出生日期：1982-02-25
- 职务：Vice Dean
- 性别：男
- 职称：教授
- 所属院系：药物科学与技术学院
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· Hadiatullah H., Lin L., Wang Z., Sundarraj R., Wang Q., Lai X., Kurebayashi N., Kobayashi T., Yamazawa T., Chen YS., Wang W., Zhao H., Yin Y., Murayama T., Van Petegem F., Yuchi Z*., Crystal structures of Ryanodine Receptor reveal dantrolene and azumolene interactions guiding inhibitor development. Nature Communication 2025. Accepted
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· Cui, X., Zheng, Y., Liu, Y., Yuchi, Z.*, Yuan, Y.* AI-driven de novo enzyme design: Strategies, applications, and future prospects. Biotechnol Adv.2025, doi: 10.1016/j.biotechadv.2025.108603.
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· Lin, L., Wang, C., Wang, W., Jiang, H., Murayama, T., Kobayashi, T., Hadiatullah, H., Chen, Y. S., Wu, S., Wang, Y., Korza, H., Gu, Y., Zhang, Y., Du, J., Van Petegem, F.*, and Yuchi, Z.* Cryo-EM structures of ryanodine receptors and diamide insecticides reveal the mechanisms of selectivity and resistance. Nature Communications. 2024, 15: 9056
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· Chen, W., Cao, P., Liu, Y., Yu, A., Wang, D., Chen, L., Sundarraj, R., Yuchi, Z., Gong, Y.*, Merzendorfer, H.*, Yang Q.* Structural basis for directional chitin biosynthesis. Nature. 2022, 61: 402-408.
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· Duan, Y., Wei, Y., Xing, M., Liu, J., Jiang, L., Lu, Q., Liu, X., Liu, Y., Ang, EL., Liao, RZ., Yuchi, Z.*, Zhao, H.*, Zhang, Y.* Anaerobic hydroxproline degradation involving c-n cleavage by a glycyl radical enzyme. Journal of the American Chemical Society, 2022, 144(22): 9715-9722.
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· Qin, J., Zhang, J., Lin, L., Haji-Ghassemi, O., Lin, Z., Woycechowsky, K.J., Van Petegem, F., Zhang, Y.*, Yuchi, Z.* Structures of PKA-phospholamban complexes reveal a mechanism of familial dilated cardiomyopathy. eLife. 2022, 11: e75346.
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· Lu, Q., Wei, Y., Lin, L., Liu, J., Duan, Y., Li, Y., Zhai, W., Liu, Y., Ang, E., Zhao, H.*, Yuchi, Z.*, Zhang, Y.* The Glycyl radical enzyme arylacetate decarboxylase from Olsenella scatoligenes. ACS Catalysis. 2021, 11(9): 5789–5794.
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· Ma, R., Haji-Ghassemi, O., Ma, D., Jiang, H., Lin, L., Yao, L., Samurkas, A., Li, Y., Wang, Y., Cao, P., Wu, S., Zhang, Y., Murayama, T., Moussian, B., Van Petegem, F.*,Yuchi, Z.* Structural basis for diamide modulation of ryanodine receptor. Nature Chemical Biology. 2020, 16: 1246-1254.
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· Liu, J., Wei, Y., Lin, L., Teng, L., Yin, J., Lu, Q., Chen, J., Zheng, Y., Li, Y., Xu, R., Zhai, W., Liu, Y., Liu, Y., Cao, P., Ang, E., Zhao, H.*, Yuchi, Z.*, Zhang, Y.* Two radical-dependent mechanisms for anaerobic degradation of the globally abundant organosulfur compound dihydroxypropanesulfonate. Proceedings of the National Academy of Sciences of the United States of America. 2020, 117(27): 15599-15608.
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· You, M.*, Ke,F.#, You,S. #, Wu, Z. #, Liu, Q. #, He, W. #, Baxter, S. #, Yuchi, Z. #, Vasseur, L.*, Gurr, G.*, Variation among 532 genomes unveils the origin and evolutionary history of a global insect herbivore. Nature Communications. 2020, 11: 2321.
