
龚俊波
- 教师名称:龚俊波
- 教师拼音名称:Gong Junbo
- 出生日期:1974-03-20
- 性别:男
- 职务:Vice Director of NERCICT
- 学科:Industrial Crystallization
- 职称:教授
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基本信息
研究方向
获奖情况
论文成果
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Prof. Gong has many years of experience in the research area of industrial crystallization, pharmaceutical and crystal engineering. He was an undergraduate student at Tianjin University(1991-1995), and got his Ph.D. degree from Department of Chemistry Engineering at Tianjin University(2001). Currently he is the vice director of the National Engineering Research Center of Industrial Crystallization Technology (NERCICT), which is the only national research center in crystallization field that was approved in 2009 by Chinese Ministry of Science and Technology (MOST) . He is also the vice director of Department of Chemical Engineering of School of Chemistry and Technology, Tianjin University. He is the member of the editorial board of two professional journals (Chinese Journal of Antibiotics and Frontiers of Chemical Science and Engineering). Recent honors include New Century Distinguished Young Professor Award (Ministry of Education, 2009), BeiYang Reserved Academic Program (2014) and Te-Pan Hou Chemical Engineering Youth Award (2015).
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- Functional crystals (covalent organic frameworks, metal orgaic frameworks, optical crystals, elastic crystals, etc.)
- Continuous crystallization (software development, process simulation, equipment design, product optimization, etc.)
- Spherical crystallization (agglomeration-crushing mechanism, caking behavior, etc.)
- Crystal engineering (design and screening of pharmaceutical polymorphism, co-crystals, solvates, amorphous forms, salts, MOF, COF, etc.),
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- Hou debang chemical technology innovation award (2018)
- Chinese Patent Award of Excellence (2017)
- Grand prize of the Scientific and Technological Progress Award of Tianjin (2019)
- Chinese Patent Gold Medal (2019)
- Qinghai province high-end introduction of leading talent (2017)
- Youth Science and Technology Outstanding Contribution Award of CPCIF (2017)
- Young and middle-aged leading talents in science and technology innovation of the ministry of science and technology (2018)
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- Mingyang Chen, Xinyu Liu, Changyou Yu, Menghui Yao, ShijieXu, Weiwei Tang, Xiaopeng Song, Weibing Dong, Gang Wang, Junbo Gong*. Strategy of selecting solvent systems for spherical agglomeration by theLifshitz-van der Waals acid-base approach [J]. Chemical Engineering Science, 220: 115613 (2020).
- Yifu Chen, Bo Yu, Shijie Xu, Fuyan Ma, Junbo Gong*. Core–Shell-Structured Cyclodextrin Metal–Organic Frameworks for Programmable Cargo Release[J]. ACS applied materials & interfaces, 11(18): 16280-16284 (2019).
- Dandan Han, Tarak Karmakar, Zoran Bjelobrk, Junbo Gong*, Michele Parrinello*. Solvent-mediated morphology selection of the active pharmaceutical ingredient isoniazid: Experimental and simulation studies[J]. Chemical Engineering Science, 204: 320-328 (2019).
- Lina Jia, Songgu Wu, Junbo Gong*. A tolbutamide–metformin salt based on antidiabetic drug combinations: synthesis, crystal structure analysis and pharmaceutical properties[J]. Acta Crystallographica Section C: Structural Chemistry, 75(9): 1250-1258 (2019).
- Yifu Chen, Bo Yu, Yingdan Cui, Shijie Xu, Junbo Gong*. Core–Shell Structured Cyclodextrin Metal–Organic Frameworks with Hierarchical Dye Encapsulation for Tunable Light Emission[J]. Chemistry of Materials, 31(4): 1289-1295 (2019).
- Haiyan Yang, Yang Yang, Lina Jia, Weiwei Tang, Shijie Xu, Shichao Du, Mingchen Li, Junbo Gong*. The Phase Transformation and Formation Mechanism of Isostructural Solvates: A Case Study of Azoxystrobin[J]. Crystal Growth & Design, 19(3): 1550-1558 (2019).
- Si Li, Weiwei Tang, Mengya Li, Lingyu Wang, Yang Yang, Junbo Gong*. Understanding the Role of Citric Acid on the Crystallization Pathways of Calcium Oxalate Hydrates[J]. Crystal Growth & Design, 19(6): 3139-3147 (2019).
- Lingyu Wang, Weiwei Tang, Shichao Du, Shijie Xu, Peng Shi, Songgu Wu, Junbo Gong*. Surprising Effect of Carbon Chain Length on Inducing Ability of Additives: Elusive Form- II of γ-Aminobutyric Acid (GABA) Induced by Sodium Carboxylate Additives[J]. Crystal Growth & Design, 19(7): 3825-3833 (2019).
- Shiyuan Liu, Lina Jia, Shijie Xu, Yifu Chen, Weiwei Tang, Junbo Gong*. Insight into the State Evolution of Norfloxacin as a Function of Drug Concentration in Norfloxacin-PVP/HPMC/HPMCP Solid Dispersions[J]. Crystal Growth & Design, 19(11): 6239-6251 (2019).
- Dejiang Zhang, Xinyi Wang, Joachim Ulrich, Weiwei Tang, Shijie Xu, Zhonghua Li, Sohrab Rohani*, Junbo Gong*. Control of Crystal Properties in a Mixed-Suspension Mixed-Product Removal Crystallizer: General Methods and the Effects of Secondary Nucleation[J]. Crystal Growth & Design, 19(5): 3070-3084 (2019).
- Zhenguo Gao, Yuanyi Wu, Junbo Gong, Jingkang Wang, Sohrab Rohani*. Continuous crystallization of α-form L-glutamic acid in an MSMPR-Tubular crystallizer system[J]. Journal of Crystal Growth, 507: 344-351 (2019).
- Teng Zhang, Botond Szilágyi, Junbo Gong, Zoltan K. Nagy*. Thermodynamic polymorph selection in enantiotropic systems using supersaturation-controlled batch and semi-batch cooling crystallization[J]. Crystal Growth & Design, 19(11): 6715-6726 (2019).
- Shaolei Zhao, Jie Gao, Siyang Ma, Chao Li, Yiming Ma, Yang He, Junbo Gong, Fu Zhou, Bingyuan Zhang, Weiwei Tang*. Mechanism and Modelling of Reactive Crystallization Process of Lithium Carbonate[J]. Processes, 7(5): 248 (2019).
- Estevao G. J. Macaringue, Songgu Wu, Shiyuan Liu, Shijie Xu, Junbo Gong*. Influence of the Solvent Content on the Phase Transformation of Sulfadiazine N‐Methyl Pyrrolidone Solvate[J]. Chemical Engineering & Technology, 42(7): 1435-1445 (2019).
- Xinyi Wang, Yifu Chen, Junbo Gong*, Jinze Hou. Aggregation-induced emission and polymorphism/shape/size-dependent emission behaviours of fenamates for potential drug evaluation[J]. Organic & biomolecular chemistry, 17(13): 3409-3415 (2019).
- Ning Wei, Lina Jia, Zeren Shang, Junbo Gong, Songgu Wu, Jingkang Wang, Weiwei Tang*. Polymorphism of levofloxacin: structure, properties and phase transformation[J]. CrystEngComm, 21, 6196-6207 (2019).
- Xinyi Wang, Shijie Xu, Lina Jia, Yujia Yang, Yu Liu, Junbo Gong, Songgu Wu*. Drug–drug salts of mefenamic acid olfenamic acid and piperazine to improve physicochemical properties for potential veterinary use[J]. CrystEngComm, 21(35): 5284-5291 (2019).
- Yufeng Quan, Yang Yang, Shijie Xu, Peipei Zhu, Shiyuan Liu, Lina Jia, Junbo Gong*. Insight into the role of piperazine in the thermodynamics and nucleation kinetics of the triethylenediamine–methyl tertiary butyl ether system[J]. CrystEngComm, 21(6): 948-956 (2019).
- Yu Liu, Lina Jia, Songgu Wu, Shijie Xu, Xu Zhang, Shuang Jiang, Junbo Gong*. Polymorphism and molecular conformations of nicosulfuron: structure, properties and desolvation process[J]. CrystEngComm, 21(17): 2790-2798 (2019).
- Zhonghua Li, Lina Jia, Peng Shi, Shuang Jiang, Junbo Gong, Songgu Wu*. Versatile solid forms of boscalid: insight into the crystal structures and phase transformations[J]. CrystEngComm, 21, 6838-6849 (2019).
- Zhonghua Li, Peng Shi, Yang Yang, Panpan Sun, Yan Wang, Shijie Xu, Junbo Gong*. Tuning crystallization and stability of the metastable polymorph of dl-methionine by a structurally similar additive[J]. CrystEngComm, 21, 3731-3739 (2019).
- Lina Jia, Yang Yu, Mengwei Wang, Hanzhi, Junbo Gong*. Preparation and characterization for multicomponent crystals of the antidiabetic drug gliquidone based on crystal engineering[J]. CrystEngComm, 21(10): 1617-1625 (2019).
- Dandan Han, Yan Wang, Yang Yang, Tingting Gong, Yifu Chen, Junbo Gong*. Revealing the role of a surfactant in the nucleation and crystal growth of thiamine nitrate: experiments and simulation studies[J]. CrystEngComm, 21, 3576-3585 (2019).
- Yan Wang, Shichao Du, Xuemei Wang, Mengmeng Sun, Yujia Yang, Junbo Gong*. Spherulitic growth and morphology control of lithium carbonate: the stepwise evolution of core-shell structures[J]. Powder Technology, 355: 617-628 (2019).
- Zhenguo Gao, Yuanyi Wu, Junbo Gong, Jingkang Wang, Sohrab Rohani*. Continuous crystallization of α-form L-glutamic acid in an MSMPR-Tubular crystallizer system[J]. Journal of Crystal Growth, 507: 344-351 (2019).
- Teng Zhang, Botond Szilágyi, Junbo Gong, Zoltan K. Nagy*. Thermodynamic polymorph selection in enantiotropic systems using supersaturation-controlled batch and semi-batch cooling crystallization[J]. Crystal Growth & Design, 19(11): 6715-6726 (2019).
- Shaolei Zhao, Jie Gao, Siyang Ma, Chao Li, Yiming Ma, Yang He, Junbo Gong, Fu Zhou, Bingyuan Zhang, Weiwei Tang*. Mechanism and Modelling of Reactive Crystallization Process of Lithium Carbonate[J]. Processes, 7(5): 248 (2019).
- Estevao G. J. Macaringue, Songgu Wu, Shiyuan Liu, Shijie Xu, Junbo Gong*. Influence of the Solvent Content on the Phase Transformation of Sulfadiazine N‐Methyl Pyrrolidone Solvate[J]. Chemical Engineering & Technology, 42(7): 1435-1445 (2019).
- Xinyi Wang, Yifu Chen, Junbo Gong*, Jinze Hou. Aggregation-induced emission and polymorphism/shape/size-dependent emission behaviours of fenamates for potential drug evaluation[J]. Organic & biomolecular chemistry, 17(13): 3409-3415 (2019).
- Ning Wei, Lina Jia, Zeren Shang, Junbo Gong, Songgu Wu, Jingkang Wang, Weiwei Tang*. Polymorphism of levofloxacin: structure, properties and phase transformation[J]. CrystEngComm, 21, 6196-6207 (2019).
- Xinyi Wang, Shijie Xu, Lina Jia, Yujia Yang, Yu Liu, Junbo Gong, Songgu Wu*. Drug–drug salts of mefenamic acid olfenamic acid and piperazine to improve physicochemical properties for potential veterinary use[J]. CrystEngComm, 21(35): 5284-5291 (2019).
- Yufeng Quan, Yang Yang, Shijie Xu, Peipei Zhu, Shiyuan Liu, Lina Jia, Junbo Gong*. Insight into the role of piperazine in the thermodynamics and nucleation kinetics of the triethylenediamine–methyl tertiary butyl ether system[J]. CrystEngComm, 21(6): 948-956 (2019).
- Yu Liu, Lina Jia, Songgu Wu, Shijie Xu, Xu Zhang, Shuang Jiang, Junbo Gong*. Polymorphism and molecular conformations of nicosulfuron: structure, properties and desolvation process[J]. CrystEngComm, 21(17): 2790-2798 (2019).
- Zhonghua Li, Lina Jia, Peng Shi, Shuang Jiang, Junbo Gong, Songgu Wu*. Versatile solid forms of boscalid: insight into the crystal structures and phase transformations[J]. CrystEngComm, 21, 6838-6849 (2019).
- Zhenguo Gao, Yang Wu, Yuanyi Wu, Junbo Gong, Ying Bao, Jingkang Wang, Sohrab Rohani*. Self-Induced Nucleation During the Antisolvent Crystallization Process of Candesartan Cilexetil[J]. Crystal Growth & Design, 18(12): 7655-7662 (2018).
- Ergang Liu, Meng Zhang, Hui Cui, Junbo Gong, Yongzhuo Huang, Jianxin Wang, Yanna Cui, Weibing Dong, Lu Sun, Huining He*, Victor C. Yang*. Tat-functionalized Ag-Fe3O4 nano-composites as tissue-penetrating vehicles for tumor magnetic targeting and drug delivery[J]. Acta pharmaceutica sinica B, 8(6): 956-968 (2018).
- Zhenguo Gao, Yuanyi Wu, Ying Bao, Junbo Gong, Jingkang Wang, Sohrab Rohani*. Image Analysis for In-line Measurement of Multidimensional Size, Shape, and Polymorphic Transformation of l-Glutamic Acid Using Deep Learning-Based Image Segmentation and Classification[J]. Crystal Growth & Design, 18(8): 4275-4281 (2018).
- Yanan Wu, Ling Zhou, Xia Zhang, Junbo Gong, Hongxun Hao, Qiuxiang Yin*, Zhao Wang*. Determination and Correlation of the Solubility of Acetylpyrazine in Pure Solvents and Binary Solvent Mixtures[J]. Journal of Solution Chemistry, 47(5): 950-973 (2018).
- Zhenguo Gao, Fatima Altimimi, Junbo Gong, Ying Bao*, Jingkang Wang, Sohrab Rohani*. Ultrasonic irradiation and seeding to prevent metastable liquid–liquid phase separation and intensify crystallization[J]. Crystal Growth & Design, 18(4): 2628-2635 (2018).
- Mengmeng Sun, Shichao Du, Mingyang Chen, Sohrab Rohani§Huihui Zhang, Ya Liu, PanPan Sun, Yaping Wang, Peng Shi, Shijie Xu, Junbo Gong*. Oiling-out investigation and morphology control of β-alanine based on ternary phase diagrams[J]. Crystal Growth & Design, 18(2): 818-826 (2018).
- Dandan Han, Bo Yu, Yumin Liu, Shichao Du, Sohrab Rohani, Teng Zhang, Shiyuan Liu, Peng Shi, Haisheng Wang, Lina Zhou, Junbo Gong*. Effects of Additives on the Morphology of Thiamine Nitrate: The Great Difference of Two Kinds of Similar Additives[J]. Crystal Growth & Design, 18(2): 775-785 (2018).
- Shijie Xu, Yifu Chen, Junbo Gong*. Jingkang Wang, Interplay between Kinetics and Thermodynamics on the Probability Nucleation Rate of a Urea–Water Crystallization System[J]. Crystal Growth & Design, 18(4): 2305-2315 (2018).
- Shasha Jin, Mingyang Chen, Zhenfang Li, Songgu Wu, Shichao Du, Shijie Xu, Sohrab Rohani, Junbo Gong*. Design and mechanism of the formation of spherical KCl particles using cooling crystallization without additives[J]. Powder Technology, 329: 455-462 (2018).
- Xiaoyan Fu, Dejiang Zhang, Shijie Xu, Bo Yu, Keke Zhang, Sohrab Rohani, Junbo Gong*. Effect of Mixing on the Particle Size Distribution of Paracetamol Continuous Cooling Crystallization Products Using a Computational Fluid Dynamics–Population Balance Equation Simulation[J]. Crystal Growth & Design, 18(5): 2851-2863 (2018).
- Keke Zhang, Shijie Xu, Shiyuan Liu, Weiwei Tang, Xiaoyan Fu, Junbo Gong*. Novel Strategy to Control Polymorph Nucleation of Gamma Pyrazinamide by Preferred Intermolecular Interactions during Heterogeneous Nucleation[J]. Crystal Growth & Design, 18(9): 4874-4879 (2018).
- Mingyang Chen, Songgu Wu, Shijie Xu, Bo Yu, Mohannad Shilbayeh, Ya Liu, Xiaowen Zhu, Jingkang Wang, Junbo Gong*. Caking of crystals: Characterization, mechanisms and prevention[J]. Powder Technology, 337: 51-67 (2018).
- Peng Shi, Shijie Xu, Shichao Du, Sohrab Rohani, Shiyuan Liu, Weiwei Tang, Lina Jia, Jingkang Wang, Junbo Gong*. Insight into Solvent-Dependent Conformational Polymorph Selectivity: The Case of Undecanedioic Acid[J]. Crystal Growth & Design,18(10): 5947-5956 (2018).
- Shiyuan Liu, Shijie Xu, Weiwei Tang, Bo Yu, Baohong Hou, Junbo Gong*. Revealing the roles of solvation in D-mannitol's polymorphic nucleation[J]. CrystEngComm, 20(46): 7435-7445 (2018).
- Weiwei Tang, Mingtao Zhang, Huaping Mo, Junbo Gong*, Jingkang Wang, Tonglei Li. Higher-order self-assembly of benzoic acid in solution[J]. Crystal Growth & Design, 17: 5049-5053 (2017).
- Weiwei Tang, Huaping Mo, Mingtao Zhang, Junbo Gong*, Jingkang Wang, Tonglei Li. Glycine’s pH-Dependent Polymorphism: A Perspective from Self-Association in Solution[J]. Crystal Growth & Design, 17: 5028-5033 (2017).
- Teng Zhang, Yumin Liu, Shichao Du, Songgu Wu, Dandan Han, Shiyuan Liu, Junbo Gong*. Polymorph control by investigating the effects of solvent and supersaturation on clopidogrel hydrogen sulfate in reactive crystallization[J]. Crystal Growth & Design, 17: 6123-6131 (2017).
- Panpan Sun, Yaping Wang, Sohrab Rohani, Ergang Liu, Shichao Du, Shijie Xu, Mingyang Chen, Zhenping Wei, Junbo Gong*. Controlled Recrystallization of Tubular Vinpocetine Crystals with Increased Aqueous Dissolution Rate and In Vivo Bioavailability[J]. Crystal Growth & Design, 17: 5790-5800 (2017).
- Weiwei Tang, Huaping Mo, Mingtao Zhang, Sean Parkin, Junbo Gong*, Jingkang Wang, Tonglei Li, Persistent self-association of solute molecules in solution[J]. The Journal of Physical Chemistry B, 121: 10118-10124 (2017).
- Bo Yu, Jie Hou, Junbo Gong*. Amorphous Co (MeIm) 2 framework coating on AuCo for size-selective photocatalysis and interface transfer[J]. Catalysis Science & Technology, 7: 5004-5010 (2017).
- Jie Hou, Chunlei Guo, Yuzhi Shi, Ergang Liu, Weibing Dong, Bo Yu, Shiyuan Liu, Junbo Gong*. A novel high drug loading mussel-inspired polydopamine hybrid nanoparticle as a pH-sensitive vehicle for drug delivery[J]. International journal of pharmaceutics, 533: 73-83 (2017).
- Shichao Du, Yan Wang, Songgu Wu, Bo Yu, Peng Shi, Lin Bian, Dejiang Zhang, Jie Hou, Jingkang Wang, Junbo Gong*. Two novel cocrystals of lamotrigine with isomeric bipyridines and in situ monitoring of the cocrystallization[J]. European Journal of Pharmaceutical Sciences, 110: 19-25 (2017).
- Zhilong Luo, Yingdan Cui, Weibing Dong, Qipeng Xu, Gaoxing Zou, Chao Kang, Baohong Hou, Song Chen, Junbo Gong*. Morphological diversity of nitroguanidine crystals with enhanced mechanical performance and thermodynamic stability[J]. Journal of Crystal Growth, 480: 132-140 (2017).
- Lina Jia, Shijie Xu, Shiyuan Liu, Shichao Du, Songgu Wu, Junbo Gong*. Polymorphs of daidzein and intermolecular interaction effect on solution crystallization[J]. CrystEngComm, 19: 7146-7153 (2017)
- Dejiang Zhang, Shijie Xu, Shichao Du, Jingkang Wang, Junbo Gong*. Progress of pharmaceutical continuous crystallization[J]. Engineering, 3: 354-364 (2017).
- 1、 Songgu Wu, Junbo Gong*, etc. Solvent penetration mediated phase transformation for the preparation of aggregated particles with well-defined shape. Cryst EngComm. 18(48): 9223-9226 (2016).2019
- 15、 Weiwei Tang, Junbo Gong*, etc. Solubility of androstenedione in lower alcohols. Fluid Phase Equilibrium. 363:86– 96 (2014) .2019
- 2、 Shijie Xu, Junbo Gong*, etc. Nucleation behavior of eszopiclone-butyl acetate solutions from metastable zone widths. Chemical Engineering Science. , 155: 248-257 (2016).2019
- 14、 Wei Du, Junbo Gong*, etc. Solution-mediated polymorphic transformation of prasugrel hydrochloride from form II to form I. Industrial & Engineering Chemistry Research. 53(14): 5652-5659 (2014) .2019
- 3、 Bo yu, Junbo Gong*, etc. Phase Transfer Directed Synthesis of Hollow Zeolitic Imidazolate Frameworks-67 Nanocages. Crystal Growth & Design. 17(1):3-6 (2017).2019
- 6、 Ze Liu, Junbo Gong, etc. Legumain protease-activated TAT-liposome cargo for targeting tumours and their microenvironment. Nature communications. 5: 4280 (2014).2019
- 7、 Wei Du, Junbo Gong*, etc. Concomitant Polymorphism of Prasugrel Hydrochloride in Reactive Crystallization. Industrial and Engineering Chemistry Research. 52(46): 16182-16189 (2013).2019
- 8、 Songgu Wu, Junbo Gong*, etc. Agglomeration Mechanism of Azithromycin Dihydrate in Acetone−Water Mixtures and Optimization of the Powder Properties. Industrial and Engineering Chemistry Research. 55(17): 4905-4910 (2016).2019
- 9、 Kangli Li, Junbo Gong*, etc. Oiling out and Polymorphism Control of Pyraclostrobin in Cooling Crystallization. Industrial and Engineering Chemistry Research. 55(44): 11631-11637 (2016) .2019
- 10、 Penglei Cui, Junbo Gong*, etc. Polymorphic Crystallization And Transformation of Candesartan Cilexetil. Industrial and Engineering Chemistry Research. 51(39): 12910–12916 (2012).2019
- 11、 Runyan Li, Junbo Gong*, etc. Correlation of Solubility and Prediction of the Mixing Properties of Ginsenoside Compound K in Various Solvents. Industrial & Engineering Chemistry Research. 51(23): 8141-8148 (2012).2019
- 5、 Yajuan Sun, Junbo Gong*, etc. Template synthesis of PMAA@chitosan hollow nanorods for docetaxel delivery. Polymer Chemistry. 4(8): 2489-2495 (2013).2019
- 4、 Mingyang Chen, Junbo Gong*, etc. Caking and adhesion free energy of maltitol: Studying of mechanism in adhesion process. Powder Technology. 272: 235-240 (2015).2019
- 12、 Bo Yu, Junbo Gong*, etc. Self-template synthesis of core–shell ZnO@ ZIF-8 nanospheres and the photocatalysis under UV irradiation. Materials Letters. 156: 50-53 (2015).2019
- 13、 Liangcheng Song, Junbo Gong*, etc. Measurement and correlation of solubility of clopidogrel hydrogen sulfate (metastable form) in lower alcohols. Journal of Chemical & Engineering Data. 56(5): 2553-2556 (2011).2019
教育经历
- 1995.9-2001.6 Tianjin University Chemical engineering Doctor of Engineering
- 1991.9-1995.6 Tianjin University Technical Economy Bachelor of Management
- 1991.9-1995.6 Tianjin University industrial chemistry Bachelor of Engineering
工作经历
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2016.11 -2019.12
|National institute of crystal science and engineering international joint research center|executive director
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2008.2 -2019.12
|National Engineering Research Center of Industrial Crystallization Technology(NERCICT)|Tianjin University|vice director
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2008.2 -2019.12
|school of chemical engineering|Tianjin University|vice director
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2008.2 -2019.12
|school of chemical engineering|Tianjin university|professor,master's supervisor
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2006.9 -2008.1
|school of pharmacy|University of Michigan|post-doctoral
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2004.7 -2006.9
|school of chemical engineering|Tianjin University|associate professor
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2001.4 -2004.7
|postdoctoral research station|Tianjin teda economic and technological development zone|post-doctoral
专利成果
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