Gong Xiaoqun
School
School of Life Sciences
Professional Title
Professor
Discipline
纳米生物诊断与治疗技术
Contact Information
gongxiaoqun@tju.edu.cn
No.92 Weijin Road, Nankai District, Tianjin, China
300072
Education Background
- Johns Hopkins University| 医学| 2012
- Master’s Degree| Tianjin University| School of Material Science and Engineering| 2009
- Doctoral degree| Tianjin University| Schoole of Material Science and Engineering| 2013
- Bachelor’s Degree| Tianjin University| School of Material Science and Engineering| 2007
Research Interests
- DNA存储新技术构建
- The detection of biomolecules(such as nucleic acid, protein) bsaed on the micro- and nano- technology;
- The thearpy of disease in the organs with mucus covered based on the mucus-penetrating nanoparticles。
Positions & Employments
-
生命科学学院 | 天津大学 | 学院党委委员 | 教授 
Academic Achievements
- Papers
- [1] Lin Su, Xiaoqun Gong*, Ruiyan Fan, Tianwen Ni, Fuhua Yang, Xiaomin Zhang a*, Xiaorong Li*, Mechanism of action of platinum nanoparticles implying from antioxidant to metabolic programming in light-induced retinal degeneration model, Redox Biology, 2023, 65:102836.(一区,11.4)
- [2] Weipan Peng, Shenghui Li, Yating zhang, Qiuting Zhang, Wenna Li, Houyu Han, Ran Luo, Jin Chang* , Xiaoqun Gong*,A Double DNAzyme-loaded MnO2 Versatile Nanodevice for Precise Cancer Diagnosis and Self-Sufficient Synergistic Gene Therapy,Chemical Engineering Journal, 2022, 450,:138138. (一区, IF=15.1)
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- [3] Han Houyu, Cui jingyu, Zhou Dianming, Hua Deping, Lin Mengyao, Zhang yating, Li Fangya, Chang Jin, Gong Xiaoqun*, Zhang Jianyu*. Single-stranded RNA as primers of terminal deoxynucleotidyl transferase for template-independent DNA polymerization. Chinese Chemical Letters (2022). (二区, IF= 8.5)
- [4] Ran Luo, Guowei Lian, Hengxuan Li, Houyu Han, Dianming Zhou, Xiaoqun Gong*. Ultrasensitive sensing of T4 PNK phosphatase activity through establishing a novel transcription-based signal amplification platform. Sensors and Actuators: B. Chemical, 2022, 369:132269. (二区, IF= 9.2)
- [5] Weipan Peng #, Xiaoqun Gong*, Dianming Zhou, Wenna Li, Minghui Chen, Guowei Lian, Jin Chang*, and Tao Wang*. MicroRNA-Responsive DNA-Programmed Nanomedicine with Controllability of Cascaded Events for Cancer Therapy Enhancement.2021,10,654-661,ACS Macro Letters(二区, IF=7.0)
- [6] Lu Li,Shenghui Li, Sheng Wang , Xiaoli Xing, Yating Zhang, Lin Su, Xiaoli Wu, Hanjie Wang, Jin Chang*, Xiaoqun Gong*, Antioxidant and anti-glycated TAT-modified platinum nanoclusters as eye drops for non-invasive and painless relief of diabetic cataract in rats. Chemical Engineering Journal, 2020, 398:125436. (一区, IF= 13.65)
- [7] Minghui Chen, Hengxuan Li, Zhihonng Shi, Xiyu Li, Weipan Peng, Yi Qin , Guowei Lian, Dianming Zhou, Xiaoqun Gong*, Jin Chang*. High Fluorescence Quenching Probe-Based Reverse Fluorescence Enhancement LFTS Coupling with IS-primer Amplification Reaction for the Rapid and Sensitive Parkinson Disease-associated MicroRNA Detection, Biosensors & Biolelectronics, 2020, 165:112278. (一区, IF=10.25)
- [8] Weipan Peng; Yi Qin; Wenna Li; Minghui Chen; Dianming Zhou; Hengxuan Li; Jingyu Cui; Jin Chang*; Sheng Xie*; Xiaoqun Gong*; Benzhong Tang. Nonenzyme Cascaded Amplification Biosensor Based on Effective Aggregation Luminescence Caused by Disintegration of Silver Nanoparticles. ACS sensors,2020, 5(7):1912-1920(一区, IF=7.3)
- [9] Jingyu Cui; Houyu Han; Jiafang Piao; Hai Shi; Dianming Zhou; Xiaoqun Gong*; Jin Chang* The construction of a novel biosensor based on the dual-enzyme cascade amplification-induced copper nanoparticles self-assembly for ultrasensitive detection of microRNA153. ACS Applied Materials & Interfaces,2020,12(30):34130-34136. (一区, IF= 8.7)
- [10] Minghui Chen, Ran Luo, Shenghui Li, Hengxuan Li, Yi Qin, Dianming Zhou,* Hao Liu, Xiaoqun Gong*, and Jin Chang*,Paper-Based Strip for Ultrasensitive Detection of OSCC-Associated Salivary MicroRNA via CRISPR/Cas12a Coupling with IS-Primer Amplification Reaction. Analytical chemistry,2020,92,13336-13342. (一区, IF= 8.7)
- [11] Weipan Peng, Qian Zhao, Minghui Chen, Jiafang Piao, Weichen Gao, Xiaoqun Gong*, Jin Chang*,An innovative “unlocked mechanism” by a double key avenue for one-pot detection of microRNA-21 and microRNA-141, Theranostics, 2019,9(1):279-289.(一区, IF= 11.3)
- [12] Qian Zhao, Jiafang Piao, Weipan Peng, Jun wang, Weichen Gao, Xiaoqun Gong*, Bingbo Zhang and Jin Chang*, A Metal Chelator as a Plasmonic Signal-Generation Superregulator for Ultrasensitive Colorimetric Bioassays of Disease Biomarkers, Advanced Science, 2018, 2018, 5(7): 1800295.(一区, IF=16.4)
- [13] Yudong Wu, Weisheng Guo, Weipan Peng, Qian Zhao, Jiafang Piao, Bo Zhang, Xiaoli Wu, Hanjie Wang, Xiaoqun Gong*, and Jin Chang*. Enhanced Fluorescence ELISA Based on HAT Triggering Fluorescence “Turn-on” with Enzyme-Antibody Dual Labeled AuNP Probes for Ultrasensitive Detection of AFP and HBsAg. ACS Applied Materials & Interfaces, 2017, 9 (11):9369–9377. (一区, IF=7.50)
- [14] Jian Zhang, Qian Zhao, Yudong Wu, Bo Zhang, Weipan Peng, Jiafang Piao, Yurui Zhou, Weichen Gao, Xiaoqun Gong* and Jin Chang *. The Construction of a Novel Nucleic Acids Detection Microplatform Based on the NSET for One-step Detecting TK1-DNA and MicroRNA-21. Biosensors and Bioelectronics, 2017, 97(15):26–33. (一区, IF=10.25)
- Honors & Awards
- [1] 2020年天津大学优秀硕士学位论文指导教师
- [2] 2019年沈志康奖教金,天津大学青年教工示范岗





